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生物标志物:GRAPPA2012 年会项目进展报告。

Biomarkers: project update from the GRAPPA 2012 annual meeting.

机构信息

Department of Rheumatology, St. Vincent's University Hospital and Conway Institute for Biomolecular Research, University College, Dublin, Ireland.

出版信息

J Rheumatol. 2013 Aug;40(8):1453-4. doi: 10.3899/jrheum.130462.

DOI:10.3899/jrheum.130462
PMID:23908545
Abstract

For members of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA), an important goal has been the identification of soluble biomarkers in psoriatic arthritis that might predict the development of radiographic progression. Work over the past year has resulted in approval of a draft protocol, and an announcement is forthcoming of the outcome of an assessment process for centers that applied to manage the project. GRAPPA is now ready to commence formal negotiations with potential funding partners and intends to initiate this project in the near future.

摘要

对于银屑病和银屑病关节炎研究和评估小组(GRAPPA)的成员来说,一个重要目标是确定银屑病关节炎中的可溶性生物标志物,这些标志物可能可以预测放射学进展的发生。过去一年的工作已经促成了一份草案方案的批准,并且即将宣布申请管理该项目的中心的评估过程的结果。GRAPPA 现在已经准备好与潜在的资助伙伴进行正式谈判,并打算在不久的将来启动该项目。

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A set of serum markers detecting systemic inflammation in psoriatic skin, entheseal, and joint disease in the absence of C-reactive protein and its link to clinical disease manifestations.一组血清标志物可在无 C 反应蛋白的情况下检测银屑病皮肤、肌腱和关节疾病的全身炎症及其与临床疾病表现的关联。
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Quantitative tandem mass-spectrometry of skin tissue reveals putative psoriatic arthritis biomarkers.皮肤组织的定量串联质谱分析揭示了潜在的银屑病关节炎生物标志物。
Clin Proteomics. 2015 Jan 13;12(1):1. doi: 10.1186/1559-0275-12-1. eCollection 2015.