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拉齐斯关于痛风的病因、诊断、治疗及预后的观点。

Rhazes viewpoints about causes, diagnosis, treatment and prognosis of gout.

作者信息

Tabatabaei Seyed Mahmoud, Tabatabaei Seyed Mohammad Ali, Zamani Mohammad Mahdi, Sabetkish Nastaran, Roshani Farnaz

机构信息

Professor of Psychiatry, Medical Ethics and History of Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

J Med Ethics Hist Med. 2012 Mar 3;5:3. Print 2012.

Abstract

Gout, a medical condition of acute inflammatory joint disorders, has been recognized from the antiquity. However, the name of Rhazes, a Persian historic physician who has described the etiology, signs, symptoms, epidemiology, treatment and prevention of this malady more than a thousand year ago, hasn't been taken into consideration appropriately. In this article, we studied and reported several chapters of Alhawi which is considered the most important Rhazes's medical textbook, focussing on his hypotheses because he has described this disease more manifestly. His original manuscripts are originally written in Arabic and they hadn't been translated to Persian until 1998. We intend to compare Rhazes opinions about gout with those of the literature in the area of rheumatology. According to our findings, Rhazes documented the symptoms of gout and categorized them scientifically. His insights about the treatment of gout, side effects of pharmacotherapy and management of the patients are so interesting and wonderful. Generally most of Rhazes viewpoints about gout are correct and compatible with recent findings. More investigation on Rhazes' viewpoints can guide us to propose more reliable hypothesis and schematize cost effective studies by delving into past medical records.

摘要

痛风是一种急性炎症性关节疾病,自古以来就已被人们认识。然而,一千多年前描述了这种疾病的病因、体征、症状、流行病学、治疗和预防方法的波斯历史上的医生拉齐斯的名字,却没有得到应有的重视。在本文中,我们研究并报告了被认为是拉齐斯最重要的医学教科书《医学集成》的几个章节,重点关注他的假说,因为他对这种疾病的描述更为清晰。他的原始手稿最初是用阿拉伯语写成的,直到1998年才被翻译成波斯语。我们打算将拉齐斯关于痛风的观点与风湿病学领域的文献观点进行比较。根据我们的研究结果,拉齐斯记录了痛风的症状并对其进行了科学分类。他对痛风治疗、药物治疗副作用和患者管理的见解非常有趣且出色。总体而言,拉齐斯关于痛风的大多数观点是正确的,并且与最近的研究结果相符。对拉齐斯观点进行更多研究可以引导我们提出更可靠的假说,并通过深入研究过去的医疗记录来规划具有成本效益的研究。

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本文引用的文献

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Gout--current diagnosis and treatment.痛风——当前的诊断与治疗
Dtsch Arztebl Int. 2009 Aug;106(34-35):549-55. doi: 10.3238/arztebl.2009.0549. Epub 2009 Aug 24.
5
Gout: an evidence-based review.痛风:一项基于证据的综述。
J Clin Rheumatol. 2008 Oct;14(5 Suppl):S55-62. doi: 10.1097/RHU.0b013e3181896921.
6
Gout and nodal osteoarthritis: a case-control study.痛风与结节性骨关节炎:一项病例对照研究。
Rheumatology (Oxford). 2008 May;47(5):732-3. doi: 10.1093/rheumatology/ken087. Epub 2008 Mar 19.
8
Imaging modalities and monitoring measures of gout.痛风的影像学检查方法与监测措施
Curr Opin Rheumatol. 2007 Mar;19(2):128-33. doi: 10.1097/BOR.0b013e32801450b7.
10
The inflammatory process of gout and its treatment.痛风的炎症过程及其治疗
Arthritis Res Ther. 2006;8 Suppl 1(Suppl 1):S3. doi: 10.1186/ar1908. Epub 2006 Apr 12.

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