Olusanya A A, Adisa A O, Lawal A O, Arotiba J T
Department of Oral and Maxillofacial Surgery, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Afr J Med Med Sci. 2013 Mar;42(1):59-64.
Ameloblastoma is a benign odontogenic tumour which is locally infiltrative and may cause severe craniofacial deformities. Its epidemiology, clinical and histologic configurations are replete in local and international literature, but data about its gross surgical patterns and treatment outcome in Nigeria is sparse. We therefore describe the clinical, gross surgical configuration, histopathologic features and the outcome of management seen at a Nigerian tertiary hospital.
Records of all histologically diagnosed Ameloblastoma from January 2000 to December 2011 at the University College Hospital, Ibadan, Nigeria, were retrieved from the departments of Oral and Maxillofacial Surgery and Oral Pathology. Patients' biodata, clinical, radiographical, gross surgical and histological features of the tumours, type of treatment, mode of jaw reconstruction and post-surgical follow up period data were documented.
One hundred and sixty-three ameloblastomas were diagnosed during the study period, only 92 had complete records and were therefore included in the study. The mean age was 34.2 years (+/- 14.25) and the male to female ratio was 1:1.1. Majority of the patients were in the low socioeconomic class (67.4%). Majority of the patients (76.5%) had segmental jaw resection and reconstruction was done mainly with non-vascularised iliac crest grafts. The gross surgical configurations were described as solid, cavitated and cystic.
Despite the locally aggressive nature of ameloblastoma, patients presented late for treatment and majority of them had segmental jaw resection as a mode of treatment. Three gross surgical configurations of the specimens were described.
成釉细胞瘤是一种良性牙源性肿瘤，具有局部浸润性，可导致严重的颅面畸形。其流行病学、临床和组织学特征在国内外文献中已有充分记载，但关于尼日利亚其大体手术模式和治疗结果的数据却很稀少。因此，我们描述了在尼日利亚一家三级医院所观察到的临床情况、大体手术形态、组织病理学特征及治疗结果。
从尼日利亚伊巴丹大学学院医院口腔颌面外科和口腔病理学部门检索2000年1月至2011年12月所有经组织学诊断的成釉细胞瘤记录。记录患者的生物数据、肿瘤的临床、影像学、大体手术和组织学特征、治疗类型、颌骨重建方式及术后随访期数据。
在研究期间共诊断出163例成釉细胞瘤，只有92例有完整记录，因此被纳入研究。平均年龄为34.2岁（±14.25），男女比例为1:1.1。大多数患者处于社会经济低阶层（67.4%）。大多数患者（76.5%）接受了节段性颌骨切除，重建主要采用非血管化髂嵴骨移植。大体手术形态分为实性、空泡状和囊性。
尽管成釉细胞瘤具有局部侵袭性，但患者就诊较晚，大多数患者接受节段性颌骨切除作为治疗方式。描述了标本的三种大体手术形态。
