London Vision Clinic, London, UK.
J Refract Surg. 2013 Aug;29(8):518-25. doi: 10.3928/1081597X-20130719-08.
To determine whether centering ablations on the coaxially sighted corneal light reflex (CSCLR) in eyes with large angle kappa leads to poor visual outcomes when compared to patients with eyes with negligible angle kappa that by default would be centered on the entrance pupil. In eyes with no angle kappa, the CSCLR coincides with the entrance pupil center, whereas eyes with large angle kappa possess an offset between the CSCLR and the entrance pupil center.
This study was a retrospective case series of consecutive patients treated by hyperopic LASIK using the MEL80 excimer laser (Carl Zeiss Meditec, Jena, Germany). All ablations were centered on the CSCLR using the standard non-wavefront-guided ablation profile. Angle kappa was classified according to pupil offset defined as the distance in the corneal plane between the entrance pupil center and the corneal vertex. Eyes were divided into two discrete groups according to the pupil offset: small angle kappa for pupil offset of 0.25 mm or less (n = 30) and large angle kappa for pupil offset of 0.55 mm or greater (n = 30). Safety, accuracy, cylinder vector analysis, contrast sensitivity, vertex centered corneal aberrations, entrance pupil centered whole eye aberrometry, and night vision disturbances were compared between the two groups.
There were no statistically significant differences in safety, accuracy, induced astigmatism, contrast sensitivity, or night vision disturbances between the two groups. There was also no statistically significant difference between groups for vertex centered corneal aberrations; however, as expected, coma was higher in the large angle kappa group for entrance pupil centered aberrometry because the treatment had been centered on the CSCLR rather than the entrance pupil center.
Refractive outcomes of high hyperopic LASIK were not found to be worse for eyes where ablation was centered more than 0.55 mm from the entrance pupil as determined by CSCLR in eyes with large angle kappa. The absence of poor quality visual outcomes in cases, which by entrance pupil centration are considered significantly "decentered," supports the notion that centration relative to the CSCLR may be preferable. This provides evidence that refractive corneal ablation should not be systematically aligned with the entrance pupil center.
比较大角度 κ 眼和小角度 κ 眼,当角膜共轴光反射(CSCLR)指导消融时,哪种情况下视觉结果较差。默认情况下,小角度 κ 眼的消融中心在瞳孔中心,而大角度 κ 眼的 CSCLR 与瞳孔中心有偏移。在没有角度 κ 的眼中,CSCLR 与瞳孔中心重合,而在大角度 κ 眼中,CSCLR 与瞳孔中心之间存在偏移。
本研究是一项回顾性病例系列研究,连续治疗远视性 LASIK 的患者,使用 MEL80 准分子激光(德国卡尔蔡司 Meditec)。所有消融均以标准非波前引导消融曲线为基础,根据角膜共轴光反射(CSCLR)定位。根据瞳孔偏移量(定义为角膜平面上瞳孔中心与角膜顶点之间的距离)将角度 κ 分为两类。根据瞳孔偏移量将眼分为两组:瞳孔偏移量小于等于 0.25mm 为小角度 κ 眼(n=30),瞳孔偏移量大于 0.55mm 为大角度 κ 眼(n=30)。比较两组的安全性、准确性、柱镜矢量分析、对比敏感度、顶点中心角膜像差、瞳孔中心全眼像差和夜视障碍。
两组间安全性、准确性、诱导散光、对比敏感度或夜视障碍均无统计学差异。两组间顶点中心角膜像差也无统计学差异;然而,正如预期的那样,大角度 κ 眼的瞳孔中心像差中的彗差较高,因为治疗是根据 CSCLR 而不是瞳孔中心进行定位。
在大角度 κ 眼中,当消融中心偏离瞳孔中心超过 0.55mm 时(通过 CSCLR 确定),并未发现远视性 LASIK 的屈光结果较差。在那些按瞳孔中心定位认为明显“偏心”的病例中,没有出现低质量的视觉结果,这支持了这样一种观点,即相对于 CSCLR 的定位可能更可取。这表明,屈光性角膜消融不应系统地与瞳孔中心对齐。