Grippo John O, Chaiyabutr Yada, Kois John C
Department of Biomedical Engineering, Western New England University, Springfield, Massachusetts, USA.
J Esthet Restor Dent. 2013 Aug;25(4):265-72. doi: 10.1111/jerd.12024. Epub 2013 Apr 2.
Although there is a high prevalence of noncarious cervical lesions (NCCLs), the etiology of these lesions remains contentious.
To evaluate the combined effects of cyclic fatigue stress and biocorrosion activity on NCCLs.
Extracted premolar teeth were allocated into four groups (N = 10). Two groups were cyclically fatigue loaded (100 N; 72 cycles per minute; 9,200 cycles) and placed in either hydrochloric acid gel (pH = 0.1) or orange juice (pH = 4). The other two groups were stored in identical chemical solutions without fatigue load. The buccal-lingual width of each tooth was measured before and after testing. The depth of biocorrosion, normalized by the percentage change in buccolingual width, normalized by time (hour) was calculated. The data were analyzed using a two-way analysis of variance and Tukey's HSD multiple comparison test (α = 0.05).
Mean (SD) of the depth of biocorrosion values were as follows: teeth receiving fatigue loading with hydrochloric acid gel exposure (1.003%/hour [0.063]) revealed a significantly higher depth of biocorrosion than the fatigue-loaded group with orange juice exposure (0.511%/hour [0.281]) (p < 0.01). For the groups without fatigue loading, those with hydrochloric acid gel (0.022%/hour [0.006]) had a significantly higher depth of biocorrosion than the group with orange juice (0.009%/hour [0.004]) (p < 0.01). The cyclically fatigue-loaded teeth with hydrochloric acid gel had a significantly greater depth of biocorrosion than either group without fatigue loading (p < 0.001).
Cyclic fatigue stress-acidic biocorrosion had a significant effect on the depth of the NCCLs.
In order to manage the destructive NCCLs lesions properly, it is essential to understand the etiology of these lesions. The present study indicated that the combined mechanisms of cyclic fatigue stress and biocorrosion could contribute to the formation of NCCLs.
尽管非龋性颈部病变（NCCLs）的患病率很高，但其病因仍存在争议。
评估循环疲劳应力和生物腐蚀活性对NCCLs的综合影响。
将拔除的前磨牙分为四组（每组n = 10）。两组进行循环疲劳加载（100 N；每分钟72次循环；9200次循环），并分别置于盐酸凝胶（pH = 0.1）或橙汁（pH = 4）中。另外两组在无疲劳加载的情况下储存在相同的化学溶液中。在测试前后测量每颗牙齿的颊舌宽度。计算生物腐蚀深度，通过颊舌宽度的百分比变化进行归一化，并按时间（小时）进行归一化。使用双向方差分析和Tukey's HSD多重比较检验（α = 0.05）对数据进行分析。
生物腐蚀深度值的平均值（标准差）如下：暴露于盐酸凝胶的疲劳加载牙齿（1.003%/小时[0.063]）的生物腐蚀深度显著高于暴露于橙汁的疲劳加载组（0.511%/小时[0.281]）（p < 0.01）。对于无疲劳加载的组，暴露于盐酸凝胶的组（0.022%/小时[0.006]）的生物腐蚀深度显著高于暴露于橙汁的组（0.009%/小时[0.004]）（p < 0.01）。暴露于盐酸凝胶的循环疲劳加载牙齿的生物腐蚀深度显著大于无疲劳加载的任何一组（p < 0.001）。
循环疲劳应力-酸性生物腐蚀对NCCLs的深度有显著影响。
为了正确处理具有破坏性的NCCLs病变，了解这些病变的病因至关重要。本研究表明，循环疲劳应力和生物腐蚀的联合机制可能导致NCCLs的形成。
