Hashibe Mia, Sturgis Erich M
Division of Public Health, Department of Family & Preventive Medicine, Huntsman Cancer Institute, University of Utah School of Medicine, 375 Chipeta Way, Suite A, Salt Lake City, UT 84108, USA.
Otolaryngol Clin North Am. 2013 Aug;46(4):507-20. doi: 10.1016/j.otc.2013.05.001. Epub 2013 Jun 25.
Although tobacco prevalence is declining in most developed countries, less developed countries are still experiencing an increase in tobacco use. Thus the future burden of oral-cavity and oropharyngeal cancers in less developed countries is expected to be heavy. The incidence of human papillomavirus (HPV)-associated oropharyngeal cancer is dramatically increasing in the United States and other developed countries, although trends in less developed countries are not clear at present. HPV vaccine compliance in the United States is low, although it continues to increase each year. Increasing the HPV vaccination rate to control future HPV-associated cancer incidence remains a priority.
尽管大多数发达国家的烟草流行率在下降，但欠发达国家的烟草使用仍在增加。因此，预计欠发达国家口腔癌和口咽癌的未来负担将很重。在美国和其他发达国家，人乳头瘤病毒（HPV）相关口咽癌的发病率正在急剧上升，尽管目前欠发达国家的趋势尚不清楚。美国的HPV疫苗接种率较低，尽管每年都在持续上升。提高HPV疫苗接种率以控制未来HPV相关癌症的发病率仍然是一个优先事项。
