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钝性颅脑创伤后脑肿胀的发展速度。

Speed of development of cerebral swelling following blunt cranial trauma.

作者信息

Byard Roger W, Vink Robert

机构信息

Adelaide Centre for Neuroscience Research, School of Medical Sciences, The University of Adelaide, Adelaide, Australia.

出版信息

J Forensic Leg Med. 2013 Aug;20(6):598-600. doi: 10.1016/j.jflm.2012.12.004. Epub 2013 Jan 10.

DOI:10.1016/j.jflm.2012.12.004
PMID:23910841
Abstract

A 22-year-old male suffered severe injuries to the head, chest and abdominal cavities in a vehicle crash, with death occurring at the scene. At autopsy, the cranial cavity was opened and markedly disrupted with compound and comminuted fracturing of all bones of the skull and facial skeleton. The brain showed extensive lacerations with almost complete parenchymal disruption. However, a preserved fragment of right frontal lobe exhibited marked swelling with gyral flattening. This case could provide further evidence for prompt cerebral swelling after blunt head trauma, and is supportive of animal studies that have demonstrated rapid swelling that is most likely is related to reactive vasodilation rather than to vasogenic oedema.

摘要

一名22岁男性在车祸中头部、胸部和腹腔受重伤,当场死亡。尸检时,打开颅腔,颅骨和面部骨骼的所有骨头均有复合性和粉碎性骨折,颅腔明显破裂。大脑显示出广泛的撕裂伤,实质几乎完全破坏。然而,右额叶的一个保存下来的碎片显示出明显肿胀,脑回变平。该病例可为钝性头部外伤后迅速出现的脑肿胀提供进一步证据,并支持动物研究,这些研究表明快速肿胀很可能与反应性血管扩张而非血管源性水肿有关。

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The law and the laboratory.
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