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糖尿病患者头颈部感染的演变评估——一项病例对照研究

Evolution assessment of head and neck infections in diabetic patients--a case control study.

作者信息

Juncar Mihai, Popa Amorin R, Baciuţ Mihaela F, Juncar Raluca Iulia, Onisor-Gligor Florin, Bran Simion, Băciuţ Grigore

机构信息

Oral and Maxilofacial Surgery Department (Head of the Department: Professor Dr. MD DDS PhD Grigore Băciuţ), "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, Moţilor 33, Cluj Napoca 400001, Cluj, Romania.

Oral and Maxilofacial Surgery Department (Head of the Department: Professor Dr. MD DDS PhD Grigore Băciuţ), "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, Moţilor 33, Cluj Napoca 400001, Cluj, Romania.

出版信息

J Craniomaxillofac Surg. 2014 Jul;42(5):498-502. doi: 10.1016/j.jcms.2013.06.009. Epub 2013 Aug 2.

Abstract

This research aimed to assess the occurrence and progression of head and neck infections in diabetic compared to non-diabetic patients. A retrospective study was carried out over a period of 10 years in 899 patients with head and neck infections. The patients who met the inclusion criteria were divided into cases and controls according to the presence/absence of diabetes. Seventy-three patients (8%, 95% CI [6.45%-10.12%]) were included in the case group and 826 (92%, 95% CI [89.87%-93.55%]) were assigned to the control group. The extension of the infection proved to be significantly (p < 0.001) higher in diabetic patients compared to non-diabetic patients. The difference between the two groups was statistically significant (Mann-Whitney U statistics = 18205.500, p < 1.56 · 10(-8)). A more than 10 year history of diabetes was statistically related to a wider extent of head and neck infections (p < 0.001). Diabetes proved to be associated with large necrotic areas and the spread of head and neck infections to more than two cavities.

摘要

本研究旨在评估糖尿病患者与非糖尿病患者相比头颈部感染的发生情况及进展。对899名头颈部感染患者进行了为期10年的回顾性研究。符合纳入标准的患者根据是否患有糖尿病分为病例组和对照组。病例组纳入73名患者(8%,95%可信区间[6.45%-10.12%]),对照组纳入826名患者(92%,95%可信区间[89.87%-93.55%])。结果表明,糖尿病患者感染的范围相比非糖尿病患者显著更大(p < 0.001)。两组之间的差异具有统计学意义(曼-惠特尼U统计量 = 18205.500,p < 1.56·10⁻⁸)。糖尿病超过10年的病史与头颈部感染范围更广在统计学上相关(p < 0.001)。糖尿病与大面积坏死区域以及头颈部感染扩散至两个以上腔隙有关。

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