Mukherjee D, Lodh S K, Sengupta M, Maity A K, Mondal A K, Ghose J C
N.R.S. Medical College, Calcutta.
Indian J Pathol Microbiol. 1990 Apr;33(2):144-50.
With the aim of reducing myocardial infarction size, isosorbide dinitrate (ISDN) was tried in 27 patients of acute myocardial infarction (AMI). There was 11% reduction of infarction size, in the ISDN treated group, in comparison to that of non treated group, though the result was not statistically significant. But, many of the in-hospital complications were significantly less in the treated group. After a critical analysis of the result it was concluded that a statistically insignificant result, as regard reduction of infarction size in AMI, cannot always exclude the utility of a drug therapy in AMI.
为了减小心肌梗死面积，对27例急性心肌梗死（AMI）患者试用了硝酸异山梨酯（ISDN）。与未治疗组相比，ISDN治疗组的梗死面积减少了11%，尽管结果无统计学意义。但是，治疗组的许多院内并发症明显较少。在对结果进行批判性分析后得出结论，就AMI梗死面积减小而言，无统计学意义的结果并不总是排除药物治疗在AMI中的效用。
