Institute for Prevention and Occupational Medicine of the German Social Accident Insurance (IPA) Institute of the Ruhr-Universität Bochum, Bochum, Germany.
Occup Environ Med. 2013 Nov;70(11):810-4. doi: 10.1136/oemed-2013-101469. Epub 2013 Aug 2.
Some studies have suggested increased lung cancer risks among bakers, however the results overall were inconsistent. The authors studied lung cancer risks among bakers and baking-related occupations in the SYNERGY pooled case-control database from 16 countries.
Occupation in a baking-related job was identified from the subjects' job histories. ORs adjusted for log(age), study centre, smoking behaviour and ever employment in a job with known exposure to occupational lung carcinogens were calculated by unconditional logistic regression. Findings were stratified by sex, histological subtype of lung cancer and smoking status.
19 366 cases (15 606 men) and 23 670 control subjects (18 528 men) were included. 473 cases (415 men, 58 women) and 501 controls (437 men, 64 women) had ever worked in baking or a related job. We did not observe an increased risk for men in baking (OR 1.01; 95% CI 0.86 to 1.18). No linear trends were observed for duration of employment. Some results suggested increased lung cancer risks for women, for example, for working as a baker for >30 years and in never-smokers, but after exclusion of one study these increased risks disappeared.
The findings from this study do not suggest increased lung cancer risks in baking-related professions.
一些研究表明面包师患肺癌的风险增加，但总体结果不一致。作者研究了来自 16 个国家的 SYNERGY 汇集病例对照数据库中面包师和烘焙相关职业的肺癌风险。
从研究对象的职业历史中确定烘焙相关工作的职业。通过非条件逻辑回归计算调整对数（年龄）、研究中心、吸烟行为和曾在已知暴露于职业性肺致癌物的工作中就业的情况下，烘焙相关职业的 OR 值。按性别、肺癌组织学亚型和吸烟状况对结果进行分层。
共纳入 19366 例病例（15606 例男性）和 23670 例对照（18528 例男性）。473 例病例（415 例男性，58 例女性）和 501 例对照（437 例男性，64 例女性）曾从事过烘焙或相关工作。我们没有观察到男性从事烘焙工作的风险增加（OR 1.01；95%CI 0.86 至 1.18）。就业时间没有观察到线性趋势。一些结果表明，女性从事烘焙工作的肺癌风险增加，例如，从事烘焙工作>30 年且从不吸烟，但排除一项研究后，这些增加的风险消失了。
本研究结果表明，与烘焙相关的职业不会增加肺癌风险。
