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[淋巴滤泡性直肠炎与溃疡性结肠炎并存]

[Coexistence of lymphoid follicular proctitis and ulcerative colitis].

作者信息

Arai Osamu, Iida Takayuki, Abe Jinrou, Watanabe Fumitoshi, Nakamura Shinichi, Hanai Hiroyuki

机构信息

Hamamatsu South Hospital Center for Gastroenterology & IBD Research, Japan.

出版信息

Nihon Shokakibyo Gakkai Zasshi. 2013 Aug;110(8):1439-46.

Abstract

We describe a rare case of ulcerative colitis (UC) with lymphoid follicular proctitis (LFP) extending discontinuously from the rectum to the ascending colon. The patient was a 42-year-old female presenting with a positive fecal occult blood test. Colonoscopy revealed erosions and disappearance of vascular patterns in the ascending colon and lower rectum, together with circumferential, uniform, granular lesions in the lower rectum. Histological examinations of the rectal biopsy specimens revealed lymphoid follicles, hyperplasia, and infiltration of chronic inflammatory cells. We suspected rectal and segmental UC with LFP. Initially, the patient was managed conservatively because of the lack of symptoms; however, on developing mucoid stools and haematochezia, mesalazine administration was started. Her symptoms and endoscopic findings resolved completely. LFP is closely associated with UC. Therefore, while diagnosing and managing LFP, it is necessary to ascertain or rule out potential complications.

摘要

我们描述了一例罕见的溃疡性结肠炎(UC)合并淋巴滤泡性直肠炎(LFP),病变从直肠间断延伸至升结肠。患者为一名42岁女性,粪便潜血试验呈阳性。结肠镜检查显示升结肠和直肠下段有糜烂及血管纹理消失,直肠下段还有环形、均匀的颗粒状病变。直肠活检标本的组织学检查显示有淋巴滤泡、增生以及慢性炎性细胞浸润。我们怀疑为直肠及节段性UC合并LFP。起初,由于无症状,患者接受保守治疗;然而,出现黏液便和便血后,开始给予美沙拉嗪治疗。她的症状和内镜检查结果完全缓解。LFP与UC密切相关。因此,在诊断和处理LFP时,有必要确定或排除潜在并发症。

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