Great North Children's Hospital, Royal Victoria Infirmary, Newcastle upon Tyne, UK.
Curr Opin Support Palliat Care. 2013 Sep;7(3):303-8. doi: 10.1097/SPC.0b013e328363a607.
Long-term follow-up (LTFU) of childhood cancer survivors is important in view of their high frequency of chronic medical problems, many of which may be serious, disabling or life-threatening. Several LTFU guidelines for the care of survivors have been developed by different national groups but provide varied recommendations with areas of both agreement and of disagreement. This diversity has generated uncertainty about the ideal nature and content of LTFU.
The EU-funded PanCareSurFup project is developing pan-European guidelines for the prevention, early detection and treatment of physical or psychosocial late effects of childhood cancer and its treatment, as well as the organization of LTFU care including age-appropriate transitional care as survivors approach adulthood and optimal health-promotion advice for individual survivors and their families. The International Late Effects of Childhood Cancer Guideline Harmonization Group aims to achieve consensus concerning clinical practice guidelines for LTFU of major late effects in survivors. The overall aim is to produce harmonized recommendations of value to all the participating countries despite their potentially disparate needs and healthcare settings.
These initiatives seek to standardize and increase the efficiency of LTFU care and improve long-term health outcomes and quality of life in survivors.
考虑到儿童癌症幸存者慢性健康问题的高发率，其中许多问题可能严重、致残或危及生命，对其进行长期随访（LTFU）非常重要。不同国家的多个团体制定了儿童癌症幸存者护理的 LTFU 指南，但提供的建议存在差异，既有一致的地方，也有不一致的地方。这种多样性导致人们对 LTFU 的理想性质和内容产生了不确定性。
由欧盟资助的 PanCareSurFup 项目正在制定泛欧指南，用于预防、早期发现和治疗儿童癌症及其治疗的身体或心理社会晚期影响，以及 LTFU 护理的组织，包括幸存者接近成年和最佳健康促进建议时的年龄适当的过渡护理以及为个别幸存者及其家庭提供的建议。国际儿童癌症晚期效应指南协调小组旨在就幸存者的主要晚期效应的 LTFU 临床实践指南达成共识。总体目标是尽管参与国可能存在潜在的不同需求和医疗保健环境，但仍能为所有参与国制定有价值的协调建议。
这些举措旨在使 LTFU 护理标准化并提高效率，并改善幸存者的长期健康结果和生活质量。
