Donati Manuela, Fiani Natascia, Di Francesco Antonietta, Di Paolo Maria, Vici Manuela, Cevenini Roberto
Section of Microbiology DESOS, Policlinico S. Orsola, University of Bologna, Bologna, Italy.
New Microbiol. 2013 Jul;36(3):303-6. Epub 2013 Jun 30.
The presence of IgG and IgA antibodies to Simkania negevensis in adult Italian patients with respiratory or gastrointestinal symptoms was investigated by the microimmunofluorescence test. In patients with respiratory infections, IgG (50%) and IgA (13%) seropositivity was consistent with previous data. In patients with gastrointestinal disorders, IgG (68%) and IgA (18%) seroprevalence was significantly higher than in healthy controls. These results, in association with the previously described detection of S. negevensis in water sources, could suggest an oral route of infection other than droplets or close contact, and a possible association of S. negevensis with gastrointestinal infections.
通过微量免疫荧光试验，对患有呼吸道或胃肠道症状的成年意大利患者中针对内格夫希曼菌的IgG和IgA抗体的存在情况进行了调查。在呼吸道感染患者中，IgG（50%）和IgA（13%）血清阳性与先前数据一致。在胃肠道疾病患者中，IgG（68%）和IgA（18%）血清阳性率显著高于健康对照。这些结果，结合先前描述的在内格夫希曼菌在水源中的检测情况，可能提示除飞沫或密切接触之外的经口感染途径，以及内格夫希曼菌与胃肠道感染之间可能存在的关联。
