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双重风险?同侧同时性肾细胞癌和尿路上皮癌的保留肾单位治疗

Double jeopardy? Renal-sparing management of simultaneous ipsilateral renal cell carcinoma and urothelial carcinoma.

作者信息

Bay Benjamin N, Black Peter

机构信息

Department of Urological Sciences, University of British Columbia, Vancouver, BC.

出版信息

Can Urol Assoc J. 2013 Jul-Aug;7(7-8):E508-10. doi: 10.5489/cuaj.409.

DOI:10.5489/cuaj.409
PMID:23914271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3713153/
Abstract

The occurrence of renal cell carcinoma (RCC) and urothelial carcinoma (UC) synchronously in the same kidney is exceedingly rare. All reported cases have been managed with either nephroureterectomy or nephrectomy. We report on a patient who required renal-sparing management of his double malignancy, including open partial nephrectomy of his pT1a RCC and endoscopic laser ablation of his low-grade Ta renal pelvis UC. After 4 years, the patient is in good health and disease-free under strict surveillance. It, therefore, would appear justified to combine partial nephrectomy for RCC and endoscopic management of UC in the same kidney of an appropriately selected patient.

摘要

肾细胞癌(RCC)和尿路上皮癌(UC)在同一侧肾脏中同时发生极为罕见。所有已报道的病例均采用肾输尿管切除术或肾切除术进行治疗。我们报告了一名患者,其双原发恶性肿瘤需要保留肾单位的治疗,包括对其pT1a期肾细胞癌进行开放性部分肾切除术以及对其低级别Ta期肾盂尿路上皮癌进行内镜激光消融术。4年后,该患者在严格监测下身体健康且无疾病。因此,对于经过适当选择的患者,在同一侧肾脏中将肾细胞癌的部分肾切除术与尿路上皮癌的内镜治疗相结合似乎是合理的。

相似文献

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Can Urol Assoc J. 2013 Jul-Aug;7(7-8):E508-10. doi: 10.5489/cuaj.409.
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Acta Biomed. 2022 Jan 19;92(6):e2021380. doi: 10.23750/abm.v92i6.11768.
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引用本文的文献

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Concurrent Urothelial Carcinoma of the Bladder and Renal Cell Carcinoma of the Kidney: A Diagnostic and Therapeutic Challenge.膀胱尿路上皮癌与肾细胞癌并存:诊断与治疗挑战
Indian J Surg Oncol. 2024 Dec;15(Suppl 4):637-641. doi: 10.1007/s13193-024-02097-4. Epub 2024 Sep 20.
2
Concurrent renal cell carcinoma and urothelial carcinoma: long-term follow-up study of 27 cases.同时性肾细胞癌和尿路上皮癌:27 例长期随访研究。
World J Surg Oncol. 2018 Jan 25;16(1):16. doi: 10.1186/s12957-018-1321-x.

本文引用的文献

1
European guidelines for the diagnosis and management of upper urinary tract urothelial cell carcinomas: 2011 update.欧洲上尿路尿路上皮细胞癌诊断和治疗指南:2011 年更新版。
Eur Urol. 2011 Apr;59(4):584-94. doi: 10.1016/j.eururo.2010.12.042. Epub 2011 Jan 14.
2
A prospective, randomised EORTC intergroup phase 3 study comparing the oncologic outcome of elective nephron-sparing surgery and radical nephrectomy for low-stage renal cell carcinoma.一项前瞻性、随机、EORTC 多组间 3 期研究比较了选择性保留肾单位手术和根治性肾切除术治疗低分期肾细胞癌的肿瘤学结局。
Eur Urol. 2011 Apr;59(4):543-52. doi: 10.1016/j.eururo.2010.12.013. Epub 2010 Dec 22.
3
Oncologic control obtained after exclusive flexible ureteroscopic management of upper urinary tract urothelial cell carcinoma.单纯软性输尿管镜处理上尿路尿路上皮癌的肿瘤控制效果。
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4
Synchronous ipsilateral renal cell carcinoma and urothelial carcinoma of the renal pelvis.同步性同侧肾细胞癌和肾盂尿路上皮癌。
Can Urol Assoc J. 2009 Feb;3(1):64-6. doi: 10.5489/cuaj.1025.
5
Are we underutilizing minimally invasive approaches for upper tract urothelial carcinoma?我们是否未充分利用微创方法治疗上尿路尿路上皮癌?
Urol Oncol. 2009 Jan-Feb;27(1):75-80. doi: 10.1016/j.urolonc.2008.04.006.
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Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study.肾皮质肿瘤患者肾切除术后的慢性肾病:一项回顾性队列研究
Lancet Oncol. 2006 Sep;7(9):735-40. doi: 10.1016/S1470-2045(06)70803-8.
7
Comparison of open nephroureterectomy and ureteroscopic and percutaneous management of upper urinary tract transitional cell carcinoma.开放性肾输尿管切除术与输尿管镜及经皮治疗上尿路移行细胞癌的比较。
Urology. 2006 Jun;67(6):1181-7. doi: 10.1016/j.urology.2005.12.034.
8
[Synchronous ipsilateral renal cell carcinoma and transitional cell carcinoma: report of 2 cases].[同步性同侧肾细胞癌和移行细胞癌:2例报告]
Hinyokika Kiyo. 2006 Jan;52(1):23-6.
9
[Renal synchronous tumor: association of renal adenocarcinoma and transitional tumor of renal pelvis, in the same kidney, an exceptional discovery].[肾同步肿瘤:同一肾脏中肾腺癌与肾盂移行性肿瘤的关联,一项罕见发现]
Actas Urol Esp. 2005 Jul-Aug;29(7):711-4. doi: 10.1016/s0210-4806(05)73325-8.
10
[Synchronous renal clear-cell carcinoma and ipsilateral transitional-cell carcinoma: case report and bibliographic review].[同步性肾透明细胞癌与同侧移行细胞癌:病例报告及文献复习]
Arch Esp Urol. 2005 Jun;58(5):460-3. doi: 10.4321/s0004-06142005000500014.