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双重风险?同侧同时性肾细胞癌和尿路上皮癌的保留肾单位治疗

Double jeopardy? Renal-sparing management of simultaneous ipsilateral renal cell carcinoma and urothelial carcinoma.

作者信息

Bay Benjamin N, Black Peter

机构信息

Department of Urological Sciences, University of British Columbia, Vancouver, BC.

出版信息

Can Urol Assoc J. 2013 Jul-Aug;7(7-8):E508-10. doi: 10.5489/cuaj.409.

Abstract

The occurrence of renal cell carcinoma (RCC) and urothelial carcinoma (UC) synchronously in the same kidney is exceedingly rare. All reported cases have been managed with either nephroureterectomy or nephrectomy. We report on a patient who required renal-sparing management of his double malignancy, including open partial nephrectomy of his pT1a RCC and endoscopic laser ablation of his low-grade Ta renal pelvis UC. After 4 years, the patient is in good health and disease-free under strict surveillance. It, therefore, would appear justified to combine partial nephrectomy for RCC and endoscopic management of UC in the same kidney of an appropriately selected patient.

摘要

肾细胞癌(RCC)和尿路上皮癌(UC)在同一侧肾脏中同时发生极为罕见。所有已报道的病例均采用肾输尿管切除术或肾切除术进行治疗。我们报告了一名患者,其双原发恶性肿瘤需要保留肾单位的治疗,包括对其pT1a期肾细胞癌进行开放性部分肾切除术以及对其低级别Ta期肾盂尿路上皮癌进行内镜激光消融术。4年后,该患者在严格监测下身体健康且无疾病。因此,对于经过适当选择的患者,在同一侧肾脏中将肾细胞癌的部分肾切除术与尿路上皮癌的内镜治疗相结合似乎是合理的。

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