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英国单中心经验:使用热膨胀型金属合金支架微创治疗腹膜后纤维化。

The use of a thermoexpandable metal alloy stent in the minimally invasive management of retroperitoneal fibrosis: a single center experience from the United kingdom.

机构信息

Endourology and Stone Services, Barts Health NHS Trust , London, United Kingdom .

出版信息

J Endourol. 2014 Jan;28(1):96-9. doi: 10.1089/end.2013.0332. Epub 2013 Nov 14.

Abstract

PURPOSE

To review our experience with and the effectiveness of the ureteral Memokath 051 metallic stent for the minimally invasive management of retroperitoneal fibrosis (RPF).

PATIENTS AND METHODS

We retrospectively reviewed the records of patients with RPF who were treated between April 2008 and February 2013. Success was defined as improvement of renal function and lack of complications after stent placement. Follow-up was at 6 weeks, 3 months, 6 months, and annually thereafter.

RESULTS

A total of 14 patients were identified. The study included eight female and six male patients. Mean age was 60.2 years±8.4 standard deviation (SD). The majority of patients had idiopathic RPF (n=12, 85.7%). Stent placement was performed in 23 renal units in 14 patients, 9 (64.3%) of whom had bilateral disease. Ten (71.4%) patients had previously received medical treatment, while three (21.4%) presented with recurrent disease postureterolysis. The mean length of follow-up was 22.5 months (range 3-56 mos). Mean stricture length was 7.6 cm±6.2 SD on the right and 7.7 cm±5.1 SD (P=0.925) on the left. Patients tolerated the stents well with minimal discomfort. Ureteral obstruction was managed successfully in 78.6% of patients (n=11/14). All patients had improvement of renal function.

CONCLUSIONS

To our knowledge, this is the first study using metal stents in patients with RPF. Retrograde placement of the ureteral Memokath 051 metal stent can be considered as a promising alternative for initial or salvage postureterolysis minimally invasive management of ureteral obstruction in RPF.

摘要

目的

回顾我们使用输尿管 Memokath 051 金属支架微创治疗腹膜后纤维化(RPF)的经验和效果。

患者和方法

我们回顾性分析了 2008 年 4 月至 2013 年 2 月期间接受治疗的 RPF 患者的病历。成功的定义是放置支架后肾功能改善且无并发症。随后分别在 6 周、3 个月、6 个月和每年进行随访。

结果

共确定了 14 名患者。研究包括 8 名女性和 6 名男性。平均年龄为 60.2 岁±8.4 标准差(SD)。大多数患者为特发性 RPF(n=12,85.7%)。14 名患者中有 23 个肾脏单位进行了支架置入,其中 9 名(64.3%)为双侧病变。10 名(71.4%)患者曾接受过药物治疗,3 名(21.4%)为复发性疾病行输尿管松解术后。平均随访时间为 22.5 个月(3-56 个月)。右侧狭窄长度平均为 7.6cm±6.2 SD,左侧狭窄长度为 7.7cm±5.1 SD(P=0.925)。患者对支架耐受良好,仅有轻微不适。78.6%(n=11/14)的患者输尿管梗阻得到成功治疗。所有患者肾功能均有改善。

结论

据我们所知,这是第一项使用金属支架治疗 RPF 患者的研究。逆行放置输尿管 Memokath 051 金属支架可作为 RPF 输尿管梗阻微创治疗初始或挽救性松解术的一种有前途的替代方法。

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