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认知功能的快照:在真实住院环境中为精神分裂症和其他慢性精神障碍患者的认知功能进行高效评估而开发一种工具。

A snapshot of cognitive functioning: deriving a tool for the efficient assessment of cognition in schizophrenia and other chronic psychiatric disorders in a real-world inpatient setting.

机构信息

Macquarie Hospital, Sydney, Australia; Macquarie University, Sydney, Australia.

出版信息

Psychiatry Res. 2013 Dec 15;210(2):375-80. doi: 10.1016/j.psychres.2013.07.006. Epub 2013 Jul 31.

DOI:10.1016/j.psychres.2013.07.006
PMID:23916361
Abstract

Previous research has led to the development of short batteries of tests that efficiently measure the cognitive functioning of individuals with schizophrenia. To attempt to replicate previous findings, we applied an empirical test selection strategy to archival cognitive test data of two non-overlapping inpatient samples of individuals with schizophrenia or schizoaffective disorder (total N=110). We then extended previous findings by applying the empirical test selection strategy to the archival data of two non-overlapping inpatient samples of individuals with various psychiatric disorders (total N=149). For each sample, tests were selected by examining the relationships between individual test scores and averaged test scores representing global cognitive functioning while taking into account test administration times. Across patient samples, digit symbol coding tasks, verbal fluency tasks, and tests with a processing speed component (Trail Making Test Part A and Stroop) emerged as efficient and effective indicators of overall cognitive functioning. A brief cognitive assessment tool incorporating coding, fluency, and processing speed tasks would provide a valid and clinically useful snapshot of a patient's level of cognitive functioning if more comprehensive testing cannot be completed.

摘要

先前的研究已经开发出了一些简短的测试组合,可以有效地衡量精神分裂症患者的认知功能。为了尝试复制先前的发现,我们对两个非重叠的精神分裂症或分裂情感障碍住院患者样本的档案认知测试数据应用了实证测试选择策略(总共 N=110)。然后,我们通过将实证测试选择策略应用于两个非重叠的各种精神障碍住院患者样本的档案数据(总共 N=149),扩展了先前的发现。对于每个样本,通过检查个体测试分数与代表整体认知功能的平均测试分数之间的关系,同时考虑测试的执行时间,来选择测试。在患者样本中,数字符号编码任务、言语流畅性任务和具有处理速度成分的测试(连线测试 A 和斯特鲁普测试)成为整体认知功能的有效指标。如果不能完成更全面的测试,那么包含编码、流畅性和处理速度任务的简短认知评估工具将提供患者认知功能水平的有效且有用的快照。

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