Ihara T, Kawaguchi H, Ito M, Kamiya H, Sakurai M
Department of Pediatrics, Mie University.
Jpn J Antibiot. 1990 May;43(5):852-9.
We administered norfloxacin (NFLX) to 16 children aged 3 to 14 year-old at the dose of 5.2 to 17.2 mg/kg/day. We evaluated the efficacy and safety of NFLX in 6 children with respiratory tract infections, 8 urinary tract infections, and 2 gastrointestinal tract infections. Efficacy rate of NFLX was 93.8% and eradicated rate was 92.9%. Any adverse effects were not observed. These results suggested that NFLX could be used safely to the children.
我们对16名3至14岁的儿童给予诺氟沙星（NFLX），剂量为5.2至17.2毫克/千克/天。我们评估了NFLX对6名呼吸道感染、8名尿路感染和2名胃肠道感染儿童的疗效和安全性。NFLX的有效率为93.8%，根除率为92.9%。未观察到任何不良反应。这些结果表明NFLX可安全用于儿童。
