Kobashi Y, Matsushima T, Nakamura J, Yano T, Adachi M, Tano Y
Department of Medicine, Kawasaki Hospital, Kawasaki Medical School, Okayama, Japan.
Kekkaku. 1990 May;65(5):333-9.
In order to determine the clinical features of patients whose tubercle bacilli were found after admission, the characteristics of 23 cases (17 males, 6 females) diagnosed after admission (Group I) were compared with 16 other cases (12 males, 4 females) diagnosed before admission (Group II). The patients in Group I were more elderly and had severer underlying diseases than those in Group II. In addition, the majority of the patients of Group I showed manifestations of respiratory infections similar to bacterial pneumonia. Therefore, 14 cases (61%) in Group I were diagnosed as bacterial pneumonia on admission. Radiological findings showed that less than half of Group I showed typical X-ray findings of tuberculosis such as location of lesions in the apex and upper lung field, cavity formation, and mixture of or new and old infiltrative lesions. Also on the PPD skin test, 7 cases (30%) of Group I were negative. Due to the above results, in many cases it took more than 10 days from admission to make a final diagnosis as tuberculosis. There were several differences in findings between two groups, but there was no definite signs to diagnose all patients at the OPD. It is therefore considered to be important to keep in mind the following to prevent admission of open tuberculosis patients into a general hospital: (1) Admission of patients suspected to have open tuberculosis at the OPD should be postponed until their smears are proven negative. (2) Sputum examinations for AFB always should be carried out in patients with respiratory symptoms.
为了确定入院后发现结核杆菌的患者的临床特征,将入院后确诊的23例患者(男17例,女6例)(第一组)的特征与入院前确诊的其他16例患者(男12例,女4例)(第二组)进行比较。第一组患者比第二组患者年龄更大,基础疾病更严重。此外,第一组的大多数患者表现出与细菌性肺炎相似的呼吸道感染症状。因此,第一组中有14例(61%)患者入院时被诊断为细菌性肺炎。影像学检查结果显示,第一组中不到一半的患者表现出典型的肺结核X线表现,如病变位于肺尖和上肺野、空洞形成以及新旧浸润性病变混合。在结核菌素皮肤试验中,第一组也有7例(30%)呈阴性。由于上述结果,在许多情况下,从入院到最终诊断为肺结核需要10多天时间。两组检查结果存在一些差异,但在门诊没有明确的体征来诊断所有患者。因此,为防止开放性肺结核患者进入综合医院,牢记以下几点被认为很重要:(1)门诊疑似开放性肺结核的患者应推迟入院,直到其涂片检查被证明为阴性。(2)有呼吸道症状的患者应始终进行痰涂片抗酸杆菌检查。