Marti Yara Nishiyama, Machado Flávia Ribeiro
Department of Anesthesiology, Pain and Intensive Care, Universidade Federal de São Paulo - UNIFESP - São Paulo SP, Brazil.
Rev Bras Ter Intensiva. 2013 Apr-Jun;25(2):168-74. doi: 10.5935/0103-507X.20130029.
The use of central venous oxygen saturation (SvcO2) and arterial lactate in the diagnosis of severe tissue hypoperfusion is well established, and the optimization of these parameters is currently under investigation, particularly in patients with severe sepsis/septic shock. However, the only place for deep venous puncture or the first choice for puncture is often the femoral vein. Although venous saturation obtained from blood sampling from this catheter, instead of SvcO2, has already been used in the diagnosis of severe tissue hypoperfusion, little is known about the accuracy of the results. The venous lactate in place of arterial puncture has also been used to guide therapeutic decisions. We conducted this literature review to seek evidence on the correlation and concordance of parameters obtained by collecting femoral venous blood gases in relation to SvcO2 and arterial lactate. Few studies in the literature have evaluated the use of femoral venous oxygen saturation (SvfO2) or venous lactate. The results obtained thus far demonstrate no adequate agreement between SvfO2 and SvcO2, which limits the clinical use of SvfO2. However, the apparent strong correlation between arterial and peripheral and central venous lactate values suggests that venous lactate obtained from the femoral vein could eventually be used instead of arterial lactate, although there is insufficient evidence on which to base this procedure at this time.
中心静脉血氧饱和度(SvcO2)和动脉血乳酸用于诊断严重组织低灌注已得到充分证实,目前正在研究如何优化这些参数,尤其是在严重脓毒症/脓毒性休克患者中。然而,深静脉穿刺的唯一部位或穿刺的首选部位通常是股静脉。尽管从该导管采血获得的静脉血氧饱和度(而非SvcO2)已用于诊断严重组织低灌注,但对结果的准确性知之甚少。用静脉血乳酸替代动脉穿刺也已用于指导治疗决策。我们进行了这项文献综述,以寻找有关采集股静脉血气所获得参数与SvcO2和动脉血乳酸之间相关性和一致性的证据。文献中很少有研究评估股静脉血氧饱和度(SvfO2)或静脉血乳酸的应用。迄今为止获得的结果表明,SvfO2与SvcO2之间没有足够的一致性,这限制了SvfO2的临床应用。然而,动脉血与外周和中心静脉血乳酸值之间明显的强相关性表明,尽管目前尚无足够证据支持该操作,但最终可以用股静脉血乳酸替代动脉血乳酸。