Lotfi Navaii Mehdi, Sadjedi Hamed, Jalali Mohsen
Engineering Department, Shahed University, P. O. Box 18155-159, 3319118651 Tehran, Iran.
Australas Phys Eng Sci Med. 2013 Sep;36(3):289-300. doi: 10.1007/s13246-013-0212-2. Epub 2013 Aug 6.
Evaluation of the electrical stimulation efficiency of various stimulating waveforms is an important issue for efficient neural stimulator design. Concerning the implantable micro devices design, it is also necessary to consider the feasibility of hardware implementation of the desired waveforms. In this paper, the charge, power and energy efficiency of four waveforms (i.e. square, rising ramp, triangular and rising ramp-decaying exponential) in various durations have been simulated and evaluated based on the computational model of the auditory nerve fibers. Moreover, for a fair comparison of their feasibility, a fully integrated current generator circuit has been developed so that the desired stimulating waveforms can be generated. The simulation results show that stimulation with the square waveforms is a proper choice in short and intermediate durations while the rising ramp-decaying exponential or triangular waveforms can be employed for long durations.
评估各种刺激波形的电刺激效率是高效神经刺激器设计的一个重要问题。对于可植入微设备设计而言，还需要考虑所需波形硬件实现的可行性。本文基于听神经纤维的计算模型，对四种波形（即方波、上升斜坡波、三角波和上升斜坡 - 衰减指数波）在不同持续时间下的电荷、功率和能量效率进行了模拟和评估。此外，为了公平比较它们的可行性，开发了一个完全集成的电流发生器电路，以便能够生成所需的刺激波形。模拟结果表明，在短和中等持续时间内，方波刺激是一个合适的选择，而对于长持续时间，可以采用上升斜坡 - 衰减指数波或三角波。
