Pastoriza-Santos Isabel, Liz-Marzán Luis M
Departamento de Química Física, Campus Universitario, Universidade de Vigo, Bilbao, Spain.
Methods Mol Biol. 2013;1025:75-93. doi: 10.1007/978-1-62703-462-3_6.
The inherent properties of silica, such as optical transparency, high biocompatibility, chemical and colloidal stability, controllable porosity, and easy surface modification, provide silica materials with a tremendous potential in biomedicine. Therefore, the coating of Au nanoparticles with silica largely contributes to enhance the important applications of metal nanoparticles in biomedicine. We describe in this chapter a number of reliable strategies that have been reported for silica coating of different types of Au nanoparticles. All descriptions are based on tested protocols and are expected to provide a reference for scientists with an interest in this field.
二氧化硅的固有特性，如光学透明性、高生物相容性、化学和胶体稳定性、可控孔隙率以及易于表面改性，赋予了二氧化硅材料在生物医学领域的巨大潜力。因此，用二氧化硅包覆金纳米粒子在很大程度上有助于增强金属纳米粒子在生物医学中的重要应用。在本章中，我们描述了一些已报道的用于不同类型金纳米粒子二氧化硅包覆的可靠策略。所有描述均基于经过测试的方案，有望为该领域感兴趣的科学家提供参考。
