Nair Akshay Gopinathan, Kaliki Swathi, Ali Mohammed Javed, Naik Milind N, Vemuganti Geeta K
Ophthalmic Plastic Surgery and Ocular Oncology Services, L V Prasad Eye Institute, Road Number 2, Banjara Hills, Hyderabad, 500034, India.
Int Ophthalmol. 2014 Jun;34(3):647-50. doi: 10.1007/s10792-013-9836-1. Epub 2013 Aug 6.
We report a case of choroidal melanoma with features suggestive of orbital cellulitis. A 24-year-old Asian Indian male presented with a 20-day history of sudden loss of vision in the right eye. Edematous eyelids with complete mechanical ptosis, complete ophthalmoplegia, gross proptosis accompanied by massive chemosis, and prolapse of the inferior forniceal conjunctiva were noted. He denied perception of light in the right eye. The left eye was unremarkable. B-scan ultrasonography of the right eye showed a large dome-shaped mass filling the posterior segment suggestive of choroidal melanoma. Computed tomography confirmed those findings and showed no extraocular tumor extension. The patient was conservatively treated with systemic steroids following which the inflammation subsided. He underwent enucleation of the right eye and a diagnosis of spindle A cell choroidal melanoma was confirmed by histopathological examination. Although rare, orbital cellulitis is one of the presenting features of choroidal melanoma. Uveal melanoma-associated orbital cellulitis can be well controlled with systemic steroids, does not always indicate extraocular tumor extension, and can occur in spindle A cell melanomas.
我们报告一例具有提示眼眶蜂窝织炎特征的脉络膜黑色素瘤病例。一名24岁的亚洲印度男性,右眼突发视力丧失20天。检查发现眼睑水肿伴完全性机械性上睑下垂、完全性眼球运动麻痹、明显眼球突出并伴有大量结膜水肿以及下穹窿结膜脱垂。他否认右眼有光感。左眼未见异常。右眼B超显示一个大的圆顶形肿物充满后段,提示脉络膜黑色素瘤。计算机断层扫描证实了这些发现,且未显示眼外肿瘤扩展。患者接受全身类固醇保守治疗后炎症消退。他接受了右眼眼球摘除术,组织病理学检查确诊为梭形A细胞脉络膜黑色素瘤。虽然罕见,但眼眶蜂窝织炎是脉络膜黑色素瘤的表现特征之一。葡萄膜黑色素瘤相关的眼眶蜂窝织炎可用全身类固醇很好地控制,并不总是提示眼外肿瘤扩展,且可发生于梭形A细胞黑色素瘤。