脉络膜和睫状体坏死性恶性黑色素瘤。一项临床病理与统计学研究。

Necrotic malignant melanomas of the choroid and ciliary body. A clinicopathological and statistical study.

作者信息

Bujara K

出版信息

Graefes Arch Clin Exp Ophthalmol. 1982;219(1):40-3. doi: 10.1007/BF02159979.

Abstract

In a review of 474 malignant melanomas of the posterior uvea the incidence of totally necrotic tumors was 3.6% and of partially necrotic, 5.7%. Longer time intervals to appearance of first symptoms and enucleation, secondary glaucoma, and inflammatory exophthalmos were significantly more frequent in necrotic malignant melanomas (P less than 0.01). Histopathological examination also revealed that necrotic tumors more often had secondary angle-closure glaucoma, rubeosis iridis, cellular inflammatory infiltrates, and extraocular extension when compared to non-necrotic tumors (P less than 0.01).

摘要

在一项对474例后葡萄膜恶性黑色素瘤的回顾性研究中，完全坏死肿瘤的发生率为3.6%，部分坏死肿瘤的发生率为5.7%。坏死性恶性黑色素瘤出现首发症状和眼球摘除的时间间隔更长、继发性青光眼和炎性眼球突出明显更为常见（P<0.01）。组织病理学检查还显示，与非坏死性肿瘤相比，坏死性肿瘤更常出现继发性闭角型青光眼、虹膜红变、细胞炎性浸润和眼外扩展（P<0.01）。