Division of Cardiology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-752, Korea.
Yonsei Med J. 2013 Sep;54(5):1285-8. doi: 10.3349/ymj.2013.54.5.1285.
A 55-year-old woman presented with frequent episodes of syncope due to sinus pauses. During ambulatory Holter monitoring, atrial fibrillation and first-degree atrioventricular nodal block were observed. Magnetic resonance imaging and CT scans showed a tumor-like mass from the superior vena cava to the right atrial septum. Open chest cardiac biopsy was performed. The tumor was composed of proliferating IgG4-positive plasma cells and lymphocytes with surrounding sclerosis. The patient was diagnosed with IgG4-related sclerosing disease. Because of frequent sinus pauses and syncope, a permanent pacemaker was implanted. The cardiac mass was inoperable, but it did not progress during the one-year follow-up.
一位 55 岁女性因窦性停搏频繁出现晕厥。在动态 Holter 监测中，观察到心房颤动和一度房室传导阻滞。磁共振成像和 CT 扫描显示上腔静脉到右心房隔肿瘤样肿块。开胸心脏活检。肿瘤由增殖的 IgG4 阳性浆细胞和淋巴细胞组成，伴有周围硬化。患者被诊断为 IgG4 相关硬化性疾病。由于窦性停搏和晕厥频繁，植入了永久性起搏器。心脏肿块无法手术，但在一年的随访中没有进展。
