伴有恶性转化的假上皮瘤性角化性云母状龟头炎。

Sardesai Vidyadhar R, Agarwal Trupti D, Dalal Avinash B, Mhatre Madhulika A

Department of Dermatology, Venereology and Leprosy, Bharati Vidyapeeth University Medical College and Hospital, Pune, India.

Indian J Sex Transm Dis AIDS. 2013 Jan;34(1):38-40. doi: 10.4103/0253-7184.112871.

Pseudoepitheliomatous, keratotic and micaceous balanitis (PKMB) is a non-venereal and extremely rare pre-malignant condition characterized by silvery white plaque with micaceous scaling on glans seen in elderly uncircumcised men. Symptoms include phimosis, pain, and interference with sexual activity. Herein we present a young, 40-year-old male with PKMB of 5 years duration with deviation of urinary stream and histology showing acanthosis, hyperkeratosis with features of cellular atypia and abnormal mitosis suggestive of malignant transformation.

假上皮瘤样、角化性和云母状龟头炎（PKMB）是一种非性病性且极为罕见的癌前病变，其特征为老年未行包皮环切术男性的龟头出现伴有云母状鳞屑的银白色斑块。症状包括包茎、疼痛以及对性活动的干扰。在此，我们报告一名40岁的年轻男性，患有病程5年的PKMB，伴有尿流偏斜，组织学显示棘皮症、角化过度，伴有细胞异型性和异常有丝分裂特征，提示恶性转化。