Choudhary Sanjiv Vijay, Madnani Amrita, Singh A L
Department of Dermatology, Jawaharlal Nehru Medical College, Sawangi, Wardha, India.
Indian J Sex Transm Dis AIDS. 2013 Jan;34(1):47-9. doi: 10.4103/0253-7184.112940.
The incidence of Warfarin-induced skin necrosis (WISN) is very low 0.01-0.10%. The majority of the WISN cases appear between day 3 and 6 of onset of Warfarin therapy. The cases of late onset WISN are rarely seen. We report a case of late onset WISN in a young human immunodeficiency virus positive female patient with thrombotic pulmonary embolism and reactivation of pulmonary tuberculosis.
华法林所致皮肤坏死（WISN）的发生率非常低，为0.01%-0.10%。大多数WISN病例出现在华法林治疗开始后的第3至6天。迟发性WISN病例很少见。我们报告了一例年轻的人类免疫缺陷病毒阳性女性患者发生迟发性WISN的病例，该患者患有血栓性肺栓塞且肺结核复发。
