Dimou Vassiliki, Gerou Spyros, Papa Anna
National Reference Centre for Arboviruses, Department of Microbiology, Medical School, Aristotle University of Thessaloniki , Greece .
Vector Borne Zoonotic Dis. 2013 Oct;13(10):719-22. doi: 10.1089/vbz.2013.1318. Epub 2013 Aug 6.
To estimate the prevalence of West Nile virus (WNV) immunoglobulin G (IgG) antibodies in residents of northern Greece before the large outbreak of 2010, stored serum samples collected during 2003-2004 from 626 apparently healthy residents of northern Greece were tested. A seroprevalence of 0.62% was detected, with no statistically significant differences among the various prefectures, gender, and age groups, suggesting that the lineage 2 WNV strain that caused the outbreaks for 3 consecutive years was introduced recently. Data from the present study can be used as a threshold in future comparisons with respective data after the outbreaks to estimate and assess the public health impact, as well as for WNV evolutionary studies.
为估算2010年大规模疫情爆发前希腊北部居民中抗西尼罗河病毒（WNV）免疫球蛋白G（IgG）抗体的流行率，对2003年至2004年期间从希腊北部626名看似健康的居民中采集并储存的血清样本进行了检测。检测到血清阳性率为0.62%，各辖区、性别和年龄组之间无统计学显著差异，这表明导致连续3年疫情爆发的2型WNV毒株是近期传入的。本研究的数据可作为未来与疫情爆发后相应数据进行比较的阈值，以估算和评估对公共卫生的影响，也可用于WNV进化研究。
