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意大利东北部献血人群中西尼罗河病毒特异性抗体的血清流行率。

Seroprevalence of West Nile virus-specific antibodies in a cohort of blood donors in northeastern Italy.

机构信息

Operative Unit of Clinical Microbiology, Regional Reference Centre for Microbiological Emergencies (CRREM), S. Orsola-Malpighi University Hospital, Bologna, Italy.

出版信息

Vector Borne Zoonotic Dis. 2011 Dec;11(12):1605-7. doi: 10.1089/vbz.2011.0616. Epub 2011 Aug 25.

DOI:10.1089/vbz.2011.0616
PMID:21867418
Abstract

IgG and IgM levels against West Nile virus (WNV) were measured in 20,033 serum samples that were obtained between October 2008 to September 2009 from 9913 blood donors in the district of Ferrara, northeastern Italy. As confirmatory test, a microneutralization assay was used to detect the presence of neutralizing antibodies against WNV. Sixty-eight subjects (0.69%) were positive for anti-WNV by immunofluorescence assay. Large differences in the prevalence of antibodies to WNV were noted between towns in the area evaluated.

摘要

在 2008 年 10 月至 2009 年 9 月期间,从意大利东北部费拉拉地区的 9913 名献血者中采集了 20033 份血清样本,检测了针对西尼罗河病毒(WNV)的 IgG 和 IgM 水平。作为确证试验,使用微量中和试验检测针对 WNV 的中和抗体的存在。68 名受试者(0.69%)通过免疫荧光检测呈抗 WNV 阳性。在所评估的地区,各城镇之间WNV 抗体的流行率存在很大差异。

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