来自深山紫堇的两种新生物碱。

Two new alkaloids from Corydalis humosa.

作者信息

Zheng Xiao-Ke, Li Dan-Dan, Yan Hui, Li Meng, He Jin-Li, Feng Wei-Sheng

机构信息

a School of Pharmacy, Henan University of Traditional Chinese Medicine , Zhengzhou , 450046 , China.

出版信息

J Asian Nat Prod Res. 2013 Nov;15(11):1158-62. doi: 10.1080/10286020.2013.822369. Epub 2013 Aug 6.

DOI:10.1080/10286020.2013.822369

PMID:23919659

Abstract

Two new alkaloids, named 1,1-dimethyl-6-methoxy-7-hydroxyl-1,2,3,4-tetrahydroisoquinoline (1) and (1R)-(4-hydroxybenzyl)-7-hydroxyl-8-O-β-d-glucopyranosyl-1,2,3,4-tetrahydroisoquinoline (2), together with 11 known compounds (3-13), were isolated from the tubers of Corydalis humosa. Their structures were elucidated on the basis of their spectroscopic and chemical evidence.

摘要

从珠芽尖距紫堇的块茎中分离得到了两种新生物碱，分别命名为1,1-二甲基-6-甲氧基-7-羟基-1,2,3,4-四氢异喹啉（1）和（1R）-（4-羟基苄基）-7-羟基-8-O-β-D-吡喃葡萄糖基-1,2,3,4-四氢异喹啉（2），以及11种已知化合物（3 - 13）。根据它们的光谱和化学证据阐明了其结构。