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双胍宁A-G,来自朝鲜紫堇的六氢苯并菲啶生物碱。

Ambiguanine A-G, hexahydrobenzophenanthridine alkaloids from Corydalis ambigua var. amurensis.

作者信息

Yang Zhi-You, Jiang Bao-Hong, Teng Fu-Kang, Han Na, Liu Zhi-Hui, Zhou Jing-Jing, Wang Yu, Guo De-An, Yin Jun

机构信息

Development and Utilization Key Laboratory of Northeast Plant Materials, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.

Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 201203, China.

出版信息

Phytochemistry. 2014 Sep;105:158-63. doi: 10.1016/j.phytochem.2014.05.013. Epub 2014 Jun 7.

Abstract

Seven hexahydrobenzophenanthridine-type alkaloids, Ambiguanine A-G, along with eight known alkaloids, were isolated from tubers of Corydalis ambigua var. amurensis. Their structures were elucidated based on extensive spectroscopic analyses, with absolute configurations determined by CD experiments.

摘要

从东北延胡索块茎中分离得到7个六氢苯并菲啶型生物碱,即Ambiguinine A-G,以及8个已知生物碱。通过广泛的光谱分析阐明了它们的结构,并通过圆二色光谱实验确定了其绝对构型。

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