Doing-Harris Kristina, Meystre Stephane M, Samore Matthew, Ceusters Werner
Department of Biomedical Informatics, University of Utah, Salt Lake City, UT, USA.
Stud Health Technol Inform. 2013;192:97-101.
The past decade has witnessed an increased interest in what are called "medically unexplained syndromes" (MUS). We address the question of whether structuring the domain knowledge for MUS can be achieved by applying the principles of Ontological Realism in light of criticisms about their usefulness in areas where science has not yet led to insights univocally endorsed by the relevant communities. We analyzed whether the different perspectives held by MUS researchers can be represented without taking any particular stance and whether existing ontologies based on Ontological Realism can be further built upon. We did not find refutation of the applicability of the principles. We found the Ontology of General Medical Science and Information Artifact Ontology to provide useful frameworks for analyzing certain MUS controversies, although leaving other questions open.
在过去十年中，人们对所谓的“医学无法解释的综合征”（MUS）的兴趣与日俱增。鉴于有人批评本体实在论原则在科学尚未得出相关领域一致认可的见解的领域中实用性存疑，我们探讨了能否通过应用这些原则来构建MUS的领域知识这一问题。我们分析了是否可以在不采取任何特定立场的情况下呈现MUS研究人员持有的不同观点，以及基于本体实在论的现有本体是否可以进一步拓展。我们没有找到反驳这些原则适用性的依据。我们发现，普通医学科学本体和信息工件本体为分析某些MUS争议提供了有用的框架，尽管其他问题仍未解决。
