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Urogynaecological Symptoms among Oncological Survivors and Impact of Oncological Treatment on Pelvic Floor Disorders and Lower Urinary Tract Symptoms. A Six-Month Follow-Up Study.肿瘤幸存者的泌尿妇科症状以及肿瘤治疗对盆底功能障碍和下尿路症状的影响。一项为期六个月的随访研究。
J Clin Med. 2020 Aug 30;9(9):2804. doi: 10.3390/jcm9092804.
2
Urinary symptoms in women receiving carboplatin/paclitaxel for treatment of gynecologic cancers.接受卡铂/紫杉醇治疗妇科癌症的女性的泌尿系统症状。
Int J Gynecol Cancer. 2020 Sep;30(9):1418-1423. doi: 10.1136/ijgc-2020-001529. Epub 2020 Jul 12.
3
Comparative analysis of genitourinary function after type C1 robotic nerve-sparing radical hysterectomy versus type C2 robotic radical hysterectomy.C1 型机器人辅助保留神经的根治性子宫切除术与 C2 型机器人根治性子宫切除术对泌尿生殖功能的比较分析。
Surg Oncol. 2019 Sep;30:58-62. doi: 10.1016/j.suronc.2019.05.003. Epub 2019 May 11.
4
Urdu translation and validation of the Urogenital Distress Inventory (UDI-6) in women with urinary incontinence.《泌尿生殖系统困扰量表(UDI - 6)》在尿失禁女性中的乌尔都语翻译及效度验证
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Brachytherapy: An overview for clinicians.近距离放射治疗:临床医生概述。
CA Cancer J Clin. 2019 Sep;69(5):386-401. doi: 10.3322/caac.21578. Epub 2019 Jul 30.
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Adjuvant treatment for endometrial cancer.子宫内膜癌的辅助治疗。
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Urinary incontinence and quality of life in endometrial cancer patients after robotic-assisted laparoscopic hysterectomy with lymph node dissection.机器人辅助腹腔镜子宫切除术加淋巴结清扫术后子宫内膜癌患者的尿失禁与生活质量
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8
Ovarian cancer in the world: epidemiology and risk factors.全球卵巢癌:流行病学与风险因素
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The role of urodynamics in the management of female stress urinary incontinence.尿动力学在女性压力性尿失禁管理中的作用。
Neurourol Urodyn. 2019 Aug;38 Suppl 4:S42-S50. doi: 10.1002/nau.23865. Epub 2019 May 2.
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Diagnosis and Treatment of Ovarian Cancer.卵巢癌的诊断与治疗
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基于SWL、II-Q7和UDI-6量表评估卵巢癌和子宫内膜癌联合治疗期间及之后女性泌尿系统功能障碍及生活舒适度。

Assessment of Dysfunction in the Urinary System as Well as Comfort in the Life of Women during and after Combination Therapy Due to Ovarian and Endometrial Cancer Based on the SWL, II-Q7 and UDI-6 Scales.

作者信息

Opławski Marcin, Smoczyńska Magdalena, Grabarek Beniamin Oskar, Boroń Dariusz

机构信息

Department of Gynecology and Obstetrics with Gynecologic Oncology, Ludwik Rydygier Memorial Specialized Hospital, 31-826 Kraków, Poland.

Department of Rehabilitation Psychology, Ludwik Rydygier Collegium Medium, Mikołaj Kopernik's University CM UMK, 30-835 Bydgoszcz, Poland.

出版信息

J Clin Med. 2021 Mar 16;10(6):1228. doi: 10.3390/jcm10061228.

DOI:10.3390/jcm10061228
PMID:33809612
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8000855/
Abstract

This work aimed to assess the influence of oncological combination therapy that was done on endometrial or ovarian cancer and how the urinary system is influenced as well as the quality of life in comparison to a group of female patients after the removal of the uterus with appendages due to endometrial cancer, which did not require the supplementation of therapy after operative treatment. The study included 87 patients with endometrial cancer, where, after the removal of the uterus, there was no need for conducting adjuvant therapy (C), as well as 92 female patients with endometrial cancer or 38 patients with ovarian cancer in whom combination therapy was conducted (group A, B). The assessment of the quality of life was conducted using the questionnaires: Satisfaction Life Scale (SWLS), Incontinence Impact Questionnaire, Short Form (IIQ-7), and Urogenital Distress Inventory (UDI-6) for three, six, nine, and 12 months after the conclusion of oncological treatment. It was observed that there was a statistically significant decrease in the quality of life in female patients who underwent combination therapy in comparison to a group in whose treatment only included surgery ( < 0.05). The risk of developing urinary incontinence increases alongside an increase in the scope of the operation and in the case of supplementing treatment with brachytherapy in comparison to chemotherapy.

摘要

这项研究旨在评估针对子宫内膜癌或卵巢癌进行的肿瘤联合治疗的影响,以及与一组因子宫内膜癌切除子宫及附件后无需术后补充治疗的女性患者相比,泌尿系统受到的影响以及生活质量。该研究纳入了87例子宫内膜癌患者,这些患者在切除子宫后无需进行辅助治疗(C组),以及92例接受联合治疗的子宫内膜癌女性患者或38例接受联合治疗的卵巢癌患者(A组、B组)。在肿瘤治疗结束后的三个月、六个月、九个月和十二个月,使用以下问卷对生活质量进行评估:生活满意度量表(SWLS)、尿失禁影响问卷简表(IIQ - 7)和泌尿生殖系统困扰量表(UDI - 6)。研究发现,与仅接受手术治疗的组相比,接受联合治疗的女性患者的生活质量在统计学上有显著下降(<0.05)。与化疗相比,随着手术范围的扩大以及在补充近距离放射治疗的情况下,发生尿失禁的风险会增加。