Singh Amit Shankar, Atam Virendra, Jain Nirdesh, Yathish Besthanahalli Errapa, Patil Malagouda R, Das Liza
Department of Medicine, King George's Medical University, Lucknow, Uttar Pradesh, India.
N Am J Med Sci. 2013 Jun;5(6):371-6. doi: 10.4103/1947-2714.114170.
Atherosclerosis is related to various cardiovascular and cerebrovascular events like cerebral infarction. Recurrence of ischemic stroke is specifically related to atherosclerotic load as determined by the presence of carotid atheromatous plaques and its echogenicity.
This study was to evaluate the association of recurrence of stroke with echogenic characteristics of carotid plaque in ischemic stroke patients.
Carotid sonography using high-resolution 7.5 MHz along with gray-scale technique was done in each ischemic stroke patient to find the occurrence of plaque and its echogenicity according to Mannheim Carotid Intima-Media Thickness Consensus (2004-2006). Followup of patient done to know the recurrence of stroke during 6-month duration and its association with plaque echogenicity.
A significant association found between the presence of plaque and known cerebrovascular risk factors. Also significant association found between recurrence of stroke and echolucent character of carotid plaque in bivariate analysis (P = 0.0028).
Recurrence of stroke is related to advanced stage of atherosclerosis that is specified by carotid plaque and its characteristics. It will help us to identify groups of patients at different risk for stroke and planning better strategies to prevent such events.
动脉粥样硬化与多种心脑血管事件相关，如脑梗死。缺血性卒中的复发与动脉粥样硬化负荷密切相关，这可通过颈动脉粥样斑块的存在及其回声特性来确定。
本研究旨在评估缺血性卒中患者卒中复发与颈动脉斑块回声特征之间的关联。
根据曼海姆颈动脉内膜中层厚度共识（2004 - 2006），对每位缺血性卒中患者使用7.5 MHz高分辨率超声并结合灰阶技术进行颈动脉超声检查，以发现斑块的存在及其回声特性。对患者进行随访，以了解6个月期间卒中的复发情况及其与斑块回声的关联。
在斑块的存在与已知的脑血管危险因素之间发现了显著关联。在双变量分析中，卒中复发与颈动脉斑块的无回声特征之间也发现了显著关联（P = 0.0028）。
卒中复发与由颈动脉斑块及其特征所表明的动脉粥样硬化晚期有关。这将有助于我们识别处于不同卒中风险的患者群体，并制定更好的策略来预防此类事件。
