Bruce M S
Unit of Clinical Psychopharmacology, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, UK.
Postgrad Med J. 1990;66 Suppl 2:S18-24.
The contrast of attitudes to the psychiatric effects of caffeine between North America and Britain is highlighted. A summary of the dietary sources, pharmacology and effects on caffeine on normal subjects is given. The emphasis in normal subjects is on the acute, chronic, toxic and withdrawal effects. With this background information, a more specific evaluation of the anxiogenic effects are discussed. In conclusion, the case is made for a trial of caffeine abstention to become part of the management of anxious patients.
北美和英国对咖啡因精神影响的态度差异得到了凸显。文中给出了咖啡因的饮食来源、药理学以及对正常受试者影响的概述。在正常受试者方面，重点在于急性、慢性、毒性及戒断效应。基于这些背景信息，对咖啡因致焦虑效应进行了更具体的评估。总之，有理由尝试让戒断咖啡因成为焦虑症患者治疗的一部分。
