以 Oxone 为唯一氧化剂，氧化 2-芳基吲哚，合成 2-芳基苯并恶嗪酮。
Oxidation of 2-arylindoles for synthesis of 2-arylbenzoxazinones with oxone as the sole oxidant.
机构信息
Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University, Xi'an 710069, PR China.
出版信息
Chem Commun (Camb). 2013 Sep 25;49(74):8196-8. doi: 10.1039/c3cc44215b.
PMID:23925205
Abstract
A novel and efficient method for the oxidation of 2-arylindoles to synthesize 2-arylbenzoxazinones utilizing oxone as the sole oxidant has been developed. The reaction tolerates a wide range of functional groups and allows quick and atom-economical assembly of a variety of valuable 2-arylbenzoxazinones in high yields.
摘要
开发了一种利用氧[单]盐作为唯一氧化剂将 2-芳基吲哚氧化合成 2-芳基苯并恶嗪酮的新颖高效方法。该反应能容忍广泛的官能团，并且能够快速、原子经济性地合成多种有价值的 2-芳基苯并恶嗪酮，产率高。
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