Department of Cornea and Refractive Surgery, Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Indian J Ophthalmol. 2013 Aug;61(8):407-9. doi: 10.4103/0301-4738.116063.
Keratoconus is the most common corneal ectatic disorder, the cause of which is largely unknown. Many factors have been implicated, and the ocular allergy is being one of them. The commonly proposed pathogenesis includes the release of inflammatory mediators due to eye rubbing which may alter the corneal collagen and lead to corneal ectasias. The onset of keratoconus is often early in cases associated with allergy and routine corneal topography may detect subtle forms of keratoconus. These cases may require early keratoplasty and are at an increased risk of having acute corneal hydrops. Surgical outcomes are similar to primary keratoconus cases. However, post-operative epithelial breakdown may be a problem in these cases. Control of allergy and eye rubbing is the best measure to prevent corneal ectasias in cases of ocular allergy.
圆锥角膜是最常见的角膜扩张性疾病，其病因在很大程度上尚不清楚。许多因素都与之相关，其中眼部过敏就是其中之一。普遍提出的发病机制包括由于眼摩擦导致的炎症介质的释放，这可能会改变角膜胶原并导致角膜扩张。与过敏相关的圆锥角膜通常在早期发病，常规角膜地形学法可能会检测到轻微形式的圆锥角膜。这些病例可能需要早期进行角膜移植，并且急性角膜水肿的风险增加。手术结果与原发性圆锥角膜病例相似。然而，在这些病例中，术后上皮破裂可能是一个问题。控制过敏和眼摩擦是预防眼部过敏病例中角膜扩张的最佳措施。
