State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, PR China.
Chem Commun (Camb). 2013 Sep 25;49(74):8163-5. doi: 10.1039/c3cc43779e.
We used single molecule force spectroscopy (SMFS) to investigate the interacting force between single cysteine and amino acid transporters in eukaryotic cell membranes. We measured the transporting force of cysteine and found that its conformation on the AFM tip is important for discriminating the substrate in the transporting pathway.
我们使用单分子力谱（SMFS）技术研究真核细胞膜上单个半胱氨酸和氨基酸转运蛋白之间的相互作用力。我们测量了半胱氨酸的转运力，发现其在 AFM 针尖上的构象对于区分转运途径中的底物很重要。
