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探索单聚酰胺胺纳米药物的跨膜动力学机制——一种“力追踪”技术。

Exploring the trans-membrane dynamic mechanisms of single polyamidoamine nano-drugs a "force tracing" technique.

作者信息

Zhou Siyuan, Yang Boyu, Chen Yang, Zhang Qingrong, Cai Mingjun, Xu Haijiao, Yang Guocheng, Wang Hongda, Shan Yuping

机构信息

School of Chemistry and Life Science, Advanced Institute of Materials Science, Changchun University of Technology Changchun 130012 China

Changchun Institute of Applied Chemistry, Chinese Academy of Science Renmin St 5625 Changchun Jilin 130022 China

出版信息

RSC Adv. 2018 Feb 27;8(16):8626-8630. doi: 10.1039/c8ra00134k. eCollection 2018 Feb 23.

DOI:10.1039/c8ra00134k
PMID:35539864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9078602/
Abstract

Considerable technological success has been achieved in the drug delivery of nano-drugs for chemotherapy, but the main obstacles in understanding the drug delivery dynamic mechanisms for nano-drug applications stem from technical limitations. In this paper, we explored the trans-membrane dynamic processes of polyamidoamine nano-drugs a "force tracing" technique.

摘要

在纳米药物化疗给药方面已经取得了相当大的技术成功，但在理解纳米药物应用的给药动态机制方面的主要障碍源于技术限制。在本文中，我们采用一种“力追踪”技术探索了聚酰胺胺纳米药物的跨膜动态过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/9078602/3b7bc8cedca4/c8ra00134k-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/9078602/dd7a3812dd56/c8ra00134k-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/9078602/15904508e399/c8ra00134k-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/9078602/3b84c6fa8492/c8ra00134k-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/9078602/5049770f1872/c8ra00134k-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/9078602/3b7bc8cedca4/c8ra00134k-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/9078602/dd7a3812dd56/c8ra00134k-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/9078602/15904508e399/c8ra00134k-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/9078602/3b84c6fa8492/c8ra00134k-f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/9078602/5049770f1872/c8ra00134k-f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e17/9078602/3b7bc8cedca4/c8ra00134k-f5.jpg

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