Roy Kallol Kumar, Subbaiah Murali, Naha Moumita, Kumar Sunesh, Sharma Jai Bhagwan, Jahagirdar Nandini
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, Room No 3076, Third Floor, Teaching Block, Ansarinagar, New Delhi, 110029, India.
Arch Gynecol Obstet. 2014 Feb;289(2):337-40. doi: 10.1007/s00404-013-2994-6. Epub 2013 Aug 8.
To evaluate the efficacy of intraperitoneal bupivacaine to reduce post operative pain after diagnostic minilaparoscopy in patients with infertility.
A prospective randomized study was performed.
The study group consisted of 104 women with infertility undergoing diagnostic minilaparoscopy. At the end of the procedure, the treatment group (Group A) was given 10 mL of intraperitoneal 0.25 % bupivacaine (100 mg) and the control group (Group B) given 10 mL of intraperitoneal saline. Post operative pain was recorded with the use of a visual analog scale with scores ranging from 1 to 10 at 2, 4, 6 and 8 h intervals after the surgery. Additional analgesics given to the patients in the post operative period and any other side effects were noted.
The treatment group had significantly lower pain scores at 2, 4, 6 and 8 h after the procedure (P < 0.05). The need for post operative analgesics also was significantly lower in the treatment group (P = 0.007).
Post operative intraperitoneal bupivacaine administration is beneficial for patients undergoing diagnostic minilaparoscopy. It can significantly decrease post operative pain for up to 8 h and reduce the need for additional analgesics.
评估腹腔内注射布比卡因对不孕症患者诊断性微型腹腔镜检查术后疼痛的缓解效果。
进行一项前瞻性随机研究。
研究组由104例接受诊断性微型腹腔镜检查的不孕症女性组成。手术结束时，治疗组（A组）腹腔内注射10 mL 0.25%布比卡因（100 mg），对照组（B组）腹腔内注射10 mL生理盐水。术后使用视觉模拟评分法记录疼痛情况，评分范围为1至10分，分别于术后2、4、6和8小时记录。记录术后给予患者的额外镇痛药以及任何其他副作用。
治疗组术后2、4、6和8小时的疼痛评分显著更低（P < 0.05）。治疗组术后对镇痛药的需求也显著更低（P = 0.007）。
诊断性微型腹腔镜检查术后腹腔内注射布比卡因对患者有益。它可显著减轻术后长达8小时的疼痛，并减少额外镇痛药的需求。
