Zullo F, Pellicano M, Cappiello F, Zupi E, Marconi D, Nappi C
Department of Gynecologic and Pediatric Sciences, Reggio Calabria University, Catanzaro, Italy.
J Am Assoc Gynecol Laparosc. 1998 May;5(2):161-3. doi: 10.1016/s1074-3804(98)80083-2.
To evaluate the efficacy of intraperitoneal subdiaphragmatic instillation of 0.5% lidocaine and 0.5% bupivacaine infiltration of cannula sites to control pain after diagnostic microlaparoscopy.
Prospective, randomized study. (Canadian Task Force classification I).
Day surgery unit of Endogyn Service, Private Endoscopic Associates, Naples, and Department of Gynecologic and Pediatric Sciences, Reggio Calabria University, Catanzaro, Italy.
Forty women treated for infertility.
The treated group received 0.5% intraperitoneal subdiaphragmatic lidocaine 40 ml and 0.5% bupivacaine 5 ml infiltration of cannula insertion sites. The control group received no treatment. In all patients the procedure was performed with atropine 0.5 mg, fentanyl 0.1 mg, droperidol 5 mg, and local anesthesia. Postoperatively, depending on the need, ketoprofene 100 mg or ketorolac 30 mg was administered intramuscularly.
Postoperative pain score was evaluated by visual analog scale immediately postoperatively and 1, 3, 6, 12, 24, 36, and 48 hours afterward. The treated group had significantly lower pain scores at the end of surgery and at 1-, 3-, (p <0.01), and 6-hour intervals (p <0.05). No significant differences in scores between groups were observed starting from 6 hours postoperatively.
Postoperative intraperitoneal lidocaine and bupivacaine infiltration of cannula sites offered a detectable benefit to women undergoing diagnostic microlaparoscopy. The effect was temporary, but induced a significant decrease in the postoperative pain for approximately 6 hours.
评估腹腔内膈下注入0.5%利多卡因和套管穿刺部位0.5%布比卡因浸润对诊断性微腹腔镜检查术后疼痛的控制效果。
前瞻性随机研究。(加拿大工作组分类I级)。
意大利那不勒斯私人内镜协会Endogyn服务日间手术单元以及卡坦扎罗雷焦卡拉布里亚大学妇产科和儿科学系。
40名接受不孕症治疗的女性。
治疗组接受40毫升腹腔内膈下0.5%利多卡因和5毫升0.5%布比卡因浸润套管插入部位。对照组未接受治疗。所有患者手术时均使用0.5毫克阿托品、0.1毫克芬太尼、5毫克氟哌利多和局部麻醉。术后根据需要,肌肉注射100毫克酮洛芬或30毫克酮咯酸。
术后立即以及术后1、3、6、12、24、36和48小时通过视觉模拟量表评估术后疼痛评分。治疗组在手术结束时以及术后1、3小时(p<0.01)和6小时间隔(p<0.05)时疼痛评分显著更低。术后6小时起两组评分未观察到显著差异。
术后腹腔内利多卡因和布比卡因浸润套管穿刺部位对接受诊断性微腹腔镜检查的女性有明显益处。这种效果是暂时的,但可使术后疼痛在约6小时内显著减轻。