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将高通量筛选的威力与天然产物的化学多样性相匹配。

Matching the power of high throughput screening to the chemical diversity of natural products.

机构信息

Basic Science Program, SAIC-Frederick, Inc., Frederick National Lab, Frederick, MD 21702, USA.

出版信息

Nat Prod Rep. 2013 Oct 11;30(10):1284-98. doi: 10.1039/c3np70052f. Epub 2013 Aug 8.

Abstract

Covering up to 2013. Application of high throughput screening technologies to natural product samples demands alterations in assay design as well as sample preparation in order to yield meaningful hit structures at the end of the campaign.

摘要

涵盖至 2013 年。高通量筛选技术在天然产物样品中的应用需要改变测定设计以及样品制备,以便在实验结束时得到有意义的命中结构。

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