Faculty of Medicine, Centro Universitário Serra dos Órgãos, Teresópolis 25964-004, RJ, Brazil.
Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, RJ, Brazil.
Nutrients. 2023 Jun 27;15(13):2912. doi: 10.3390/nu15132912.
Bercht. & J. Presl has been widely used due to the presence of different bioactive compounds. This review summarizes the latest advances and perspectives of the plant species; it is a systematic literature review on aspects of botany, traditional uses, phytochemistry, pharmacology, and toxicology as therapeutic potential. In addition, 120 compounds are described, including alkaloids, flavonoids, terpenoids, steroids, amino acids, aromatics, and aliphatics. As for the therapeutic potential, it is described in extracts and compounds in the antitumor, anti-inflammatory, antioxidant, antimicrobial, antispasmodic, anticoagulant, and analgesic aspects, as well as the effects on the central nervous system. The toxicity of the genus stands out, especially the potential for organ toxicity. Therefore, this review evidenced the knowledge related to the traditional use based on the scientific research of , highlighting an overview of bioactive compounds and biological and toxicological activities in order to provide a scientific basis for future studies on the value of this species for the development of new natural products.
Bercht. & J. Presl 因其含有多种生物活性化合物而被广泛应用。本综述总结了该植物物种的最新进展和研究方向;它是一篇关于植物学、传统用途、植物化学、药理学和毒理学方面的系统文献综述,探讨了其作为治疗潜力的各个方面。此外,还描述了 120 种化合物,包括生物碱、类黄酮、萜类、甾体、氨基酸、芳香族化合物和脂肪族化合物。至于治疗潜力,它描述了提取物和化合物在抗肿瘤、抗炎、抗氧化、抗菌、抗痉挛、抗凝和镇痛方面,以及对中枢神经系统的影响。该属的毒性尤为突出,特别是对器官毒性的潜在影响。因此,本综述基于 Bercht. & J. Presl 的科学研究,对传统用途相关知识进行了总结,强调了生物活性化合物和生物及毒理学活性的概述,为未来关于该物种价值的研究提供了科学依据,以开发新的天然产物。