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脱细胞真皮基质同种异体移植物与游离牙龈移植物在种植体周围附着黏膜增量中的比较:一项随机对照试验。

The comparison of acellular dermal matrix allografts with free gingival grafts in the augmentation of peri-implant attached mucosa: a randomised controlled trial.

作者信息

Basegmez Cansu, Karabuda Zihni Cuneyt, Demirel Korkud, Yalcin Serdar

机构信息

Istanbul University, Department of Oral Implantology, Istanbul, Turkey.

出版信息

Eur J Oral Implantol. 2013 Summer;6(2):145-52.

PMID:23926586
Abstract

PURPOSE

The purpose of this randomised controlled trial is to compare the efficacy of two techniques for enhancing peri-implant keratinised mucosa: acellular dermal matrix allograft versus free gingival grafts.

MATERIALS AND METHODS

Thirty-six patients having implant sites with less than 1.5 mm of keratinised mucosa width were randomly assigned to two groups. Thirty-six implants placed in 18 patients received acellular dermal matrix allografts (ADM group), while 36 implants placed in 18 individuals received free gingival grafts (FGG group). Plaque index (PI), gingival index (GI), probing depth (PD) and the width of attached mucosa (WAM) were measured at baseline and at 1, 3 and 6 months following surgery.

RESULTS

WAM in the FGG group was significantly greater than the ADM group at 3 (P = 0.026) and 6 months (P < 0.001). In the FGG group, final gain of WAM was greater (1.58 mm in ADM group, 2.57 mm in FGG group) (P < 0.001) and postoperative relapse was smaller (2.68 mm in the ADM group, 1.73 mm in the FGG group) (P < 0.001). PI and GI scores were greater in the ADM group at 6 months (P = 0.016 and P = 0.61, respectively). The FGG group demonstrated a greater PD value at 3 months (P < 0.001), however there was no significant difference between the groups at 6 months (P = 0.317).

CONCLUSIONS

Although ADM allografts are capable of increasing the width of peri-implant keratinised mucosa, FGGs seem to be more effective. ADM allografts may be the application of choice at implant sites in need of major grafts and in patients where a donor site should be avoided for medical or psychological reasons.

摘要

目的

本随机对照试验的目的是比较两种增加种植体周围角化黏膜的技术的疗效:脱细胞真皮基质同种异体移植物与游离龈瓣移植术。

材料与方法

36例种植部位角化黏膜宽度小于1.5mm的患者被随机分为两组。18例患者植入的36颗种植体接受脱细胞真皮基质同种异体移植物(ADM组),而18例个体植入的36颗种植体接受游离龈瓣移植术(FGG组)。在基线以及术后1、3和6个月时测量菌斑指数(PI)、牙龈指数(GI)、探诊深度(PD)和附着黏膜宽度(WAM)。

结果

FGG组的WAM在3个月时(P = 0.026)和6个月时(P < 0.001)显著大于ADM组。在FGG组中,WAM的最终增加量更大(ADM组为1.58mm,FGG组为2.57mm)(P < 0.001),术后复发更小(ADM组为2.68mm,FGG组为1.73mm)(P < 0.001)。ADM组在6个月时的PI和GI评分更高(分别为P = 0.016和P = 0.61)。FGG组在3个月时的PD值更大(P < 0.001),然而两组在6个月时无显著差异(P = 0.317)。

结论

虽然ADM同种异体移植物能够增加种植体周围角化黏膜的宽度,但FGG似乎更有效。ADM同种异体移植物可能是需要大型移植物的种植部位以及因医学或心理原因应避免供区的患者的首选应用。

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