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[高嗜酸性粒细胞综合征与肾功能不全]

[Hypereosinophilic syndrome and renal insufficiency].

作者信息

Garella G, Marra L

机构信息

Istituto di Patologia Speciale Medica, Università Cattolica del Sacro Cuore, Roma.

出版信息

Minerva Urol Nefrol. 1990 Apr-Jun;42(2):135-6.

PMID:2392741
Abstract

Hypereosinophilic syndrome is a pathological condition whose etiology is still unclear. Having been introduced for the first time Hardy and Anderson in 1968, the term is used to indicate hypereosinophilia which does not accompany those pathologies with which it is more commonly associated. This paper reports the case of a patient affected by hypereosinophilic syndrome associated with kidney insufficiency. This association with a clinical picture of eosinophilic interstitial nephritis has rarely been described in the past. The Authors discuss the possibility of a possible evolution towards renal insufficiency, probably caused by the successive appearance of arteriolar glomerulitis with vasculitis, leading to the dysfunction of a growing number of nephrons.

摘要

高嗜酸性粒细胞综合征是一种病因仍不明确的病理状态。该术语由哈代和安德森于1968年首次提出,用于指不伴有那些更常见相关疾病的高嗜酸性粒细胞增多症。本文报告了一例患有高嗜酸性粒细胞综合征并伴有肾功能不全的患者病例。这种与嗜酸性间质性肾炎临床表现相关的情况过去很少被描述。作者讨论了可能发展为肾功能不全的可能性,这可能是由于小动脉肾小球炎伴血管炎的相继出现,导致越来越多的肾单位功能障碍。

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