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一名急性淋巴细胞白血病患者发生蜡样芽孢杆菌败血症:病例报告及文献复习

Bacillus cereus septicemia in a patient with acute lymphoblastic leukemia: A case report and review of the literature.

作者信息

Chou Ya-Ling, Cheng Shin-Nan, Hsieh Kao-Hsian, Wang Chih-Chien, Chen Shyi-Jou, Lo Wen-Tsung

机构信息

Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

出版信息

J Microbiol Immunol Infect. 2016 Jun;49(3):448-51. doi: 10.1016/j.jmii.2013.06.010. Epub 2013 Aug 6.

Abstract

Bacillus cereus is an aerobic Gram-positive, spore-forming, rod-shaped bacterium that is responsible for foodborne illnesses. We report on a 15-year-old girl with B-cell acute lymphoblastic leukemia, who fell into a somnolent state after presenting with a 12-hour history of fever, muscle soreness, myalgia in both calves, sore throat, and vomiting. Fulminant septicemic syndrome caused by B. cereus was finally identified. The aim of this work is the introduction of B. cereus as a differential diagnosis of sepsis in patients with acute leukemia in induction chemotherapy, to prevent delayed treatment.

摘要

蜡样芽孢杆菌是一种需氧的革兰氏阳性、形成芽孢的杆状细菌,可导致食源性疾病。我们报告了一名15岁患B细胞急性淋巴细胞白血病的女孩,她在出现发热、肌肉酸痛、双侧小腿肌痛、喉咙痛和呕吐12小时后陷入嗜睡状态。最终确诊为由蜡样芽孢杆菌引起的暴发性败血症综合征。这项工作的目的是引入蜡样芽孢杆菌作为诱导化疗的急性白血病患者败血症的鉴别诊断,以防止治疗延误。

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