Zhang Jing-Wen, Zeng Yun-Xin, Liang Jia-Yin, Zhang Ling, Zhao Xin-Bao, Pan Jian-Hua, Xiao Ruo-Zhi
Clin Lab. 2018 Oct 1;64(10):1761-1764. doi: 10.7754/Clin.Lab.2018.180528.
We herein report a fatal case of fulminant septicemia caused by Bacillus cereus in a 49-year-old female with T-cell acute lymphoblastic leukemia receiving chemotherapy.
Her two blood culture sets were positive for Gram-positive, rod-shaped bacterium. Bacillus cereus was identified by high-throughput MALDI-TOF mass spectrometry and 16S ribosomal RNA gene sequencing.
The patient died within 12 hours from the onset of B cereus infection.
Patients with acute leukemia presented with fever and unexplained multiple organ lesions, especially accompanied by CNS symptoms, should alert to the possibility of Bacillus cereus infection.
我们在此报告一例由蜡样芽孢杆菌引起的暴发性败血症致死病例，患者为一名49岁接受化疗的T细胞急性淋巴细胞白血病女性。
她的两组血培养结果显示革兰氏阳性杆状细菌呈阳性。通过高通量基质辅助激光解吸电离飞行时间质谱和16S核糖体RNA基因测序鉴定出蜡样芽孢杆菌。
患者在蜡样芽孢杆菌感染发病后12小时内死亡。
急性白血病患者出现发热和不明原因的多器官损害，尤其是伴有中枢神经系统症状时，应警惕蜡样芽孢杆菌感染的可能性。
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