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成人脑肿瘤:磁共振波谱的临床应用。

Adult brain tumors: clinical applications of magnetic resonance spectroscopy.

机构信息

Clínica Felippe Mattoso, Barra da Tijuca, Rio de Janeiro 30112011, Brazil.

出版信息

Neuroimaging Clin N Am. 2013 Aug;23(3):527-55. doi: 10.1016/j.nic.2013.03.002. Epub 2013 May 10.

DOI:10.1016/j.nic.2013.03.002
PMID:23928203
Abstract

Proton magnetic resonance spectroscopy (H-MRS) may be helpful in suggesting tumor histology and tumor grade and may better define tumor extension and the ideal site for biopsy compared with conventional magnetic resonance (MR) imaging. A multifunctional approach with diffusion-weighted imaging, perfusion-weighted imaging, and permeability maps, along with H-MRS, may enhance the accuracy of the diagnosis and characterization of brain tumors and estimation of therapeutic response. Integration of advanced imaging techniques with conventional MR imaging and the clinical history help to improve the accuracy, sensitivity, and specificity in differentiating tumors and nonneoplastic lesions.

摘要

质子磁共振波谱(H-MRS)可能有助于提示肿瘤组织学和肿瘤分级,并可能比常规磁共振成像(MR 成像)更好地定义肿瘤的范围和活检的理想部位。与 H-MRS 相结合的扩散加权成像、灌注加权成像和渗透性图的多功能方法可能会提高脑肿瘤诊断和特征描述以及治疗反应评估的准确性。将先进的成像技术与常规磁共振成像和临床病史相结合,有助于提高区分肿瘤和非肿瘤病变的准确性、敏感性和特异性。

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