成人脑肿瘤：磁共振波谱的临床应用
Adult Brain Tumors: Clinical Applications of Magnetic Resonance Spectroscopy.
作者信息
Brandão Lara A, Castillo Mauricio
机构信息
Clínica Felippe Mattoso, Av. Das Américas 700, sala 320, Barra da Tijuca, Rio de Janeiro 30112011, Brazil; Clínica IRM- Ressonância Magnética, Rua Capitão Salomão 44 Humaitá, Rio de Janeiro 22271040, Brazil.
Division of Neuroradiology, Department of Radiology, University of North Carolina School of Medicine, Room 3326, Old Infirmary Building, Manning Drive, Chapel Hill, NC 27599-7510, USA.
出版信息
Magn Reson Imaging Clin N Am. 2016 Nov;24(4):781-809. doi: 10.1016/j.mric.2016.07.005.
Proton magnetic resonance spectroscopy (H-MRS) may be helpful in suggesting tumor histology and tumor grade and may better define tumor extension and the ideal site for biopsy compared with conventional magnetic resonance (MR) imaging. A multifunctional approach with diffusion-weighted imaging, perfusion-weighted imaging, and permeability maps, along with H-MRS, may enhance the accuracy of the diagnosis and characterization of brain tumors and estimation of therapeutic response. Integration of advanced imaging techniques with conventional MR imaging and the clinical history help to improve the accuracy, sensitivity, and specificity in differentiating tumors and nonneoplastic lesions.
质子磁共振波谱（H-MRS）有助于提示肿瘤组织学类型和肿瘤分级，与传统磁共振（MR）成像相比，可能能更好地界定肿瘤范围及活检的理想部位。采用弥散加权成像、灌注加权成像、通透性图以及H-MRS的多功能方法，可能会提高脑肿瘤诊断、特征描述及治疗反应评估的准确性。将先进成像技术与传统MR成像及临床病史相结合，有助于提高鉴别肿瘤与非肿瘤性病变的准确性、敏感性和特异性。
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