Univ Paris-Sud, CNRS, BioCIS-UMR 8076, Laboratoire de Chimie Thérapeutique, LabEx LERMIT, Faculté de Pharmacie, 5 rue J.-B. Clément, Châtenay-Malabry, F-92296, France.
Chem Commun (Camb). 2013 Sep 28;49(75):8359-61. doi: 10.1039/c3cc44780d.
An efficient and practical N-arylation of glycosylamines with substituted aryl boronic acids has been established. Using Cu(OAc)2 and pyridine at room temperature under air atmosphere, the protocol proved to be general, and a variety of aryl N-glycosides have been prepared in good to excellent yields with exclusive β selectivity.
建立了一种高效实用的糖基胺与取代芳基硼酸的 N-芳基化方法。该方法在室温下、空气氛围中使用 Cu(OAc)2 和吡啶作为催化剂，具有广泛的适用性，能够以良好至优秀的收率得到各种芳基 N-糖苷，且具有独特的 β 选择性。
