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突发性聋预后因素的交互作用分析:一项回顾性研究

Prognostic factors in sudden sensorineural hearing loss: a retrospective study using interaction effects.

机构信息

Department of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, Eulji University, South Korea.

出版信息

Braz J Otorhinolaryngol. 2013 Aug;79(4):466-70. doi: 10.5935/1808-8694.20130083.

Abstract

UNLABELLED

The prognostic significance of vertigo in patients with idiopathic sudden sensorineural hearing loss (SSNHL) remains a matter of debate.

OBJECTIVE

This paper aims to verify the difference between a group with vertigo and a group without vertigo, and to analyze vertigo's validation as a prognostic factor in patients with SSNHL.

METHOD

This study involved 183 patients with SSNHL. A t-test was used to compare group A (SSNHL with vertigo, n = 31) and group B (SSNHL without vertigo, n = 152). Also we want to verify the interaction effects between vertigo and other prognostic factors using multiple regression analysis.

RESULTS

There was a significant difference between group A and group B: the initial hearing level of group A was lower than group B, and their treatment onset was also shorter. In addition, vertigo itself didn't affect hearing improvement, but the interaction variable between vertigo and initial hearing level did affect hearing improvement significantly.

CONCLUSION

The clinical characteristics of patients with vertigo did not directly affect hearing improvement with SSNHL; however, vertigo had an influence on SSNHL though its interaction with the initial hearing levels.

摘要

未加标签

眩晕在特发性突发性聋(SSNHL)患者中的预后意义仍存在争议。

目的

本文旨在验证伴有眩晕和不伴有眩晕的两组患者之间的差异,并分析眩晕作为 SSNHL 患者预后因素的验证。

方法

本研究纳入了 183 例 SSNHL 患者。采用 t 检验比较组 A(伴有眩晕的 SSNHL,n = 31)和组 B(不伴有眩晕的 SSNHL,n = 152)。还使用多元回归分析来验证眩晕与其他预后因素之间的交互效应。

结果

组 A 和组 B 之间存在显著差异:组 A 的初始听力水平低于组 B,且治疗起始时间也较短。此外,眩晕本身并不影响听力改善,但眩晕与初始听力水平之间的交互变量显著影响听力改善。

结论

眩晕患者的临床特征并不直接影响 SSNHL 的听力改善;然而,眩晕通过与初始听力水平的相互作用对 SSNHL 产生影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7a3f/9442397/49edca24d091/gr1.jpg

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